CDC6B_HALMA
ID CDC6B_HALMA Reviewed; 412 AA.
AC Q5UWY4;
DT 29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 07-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=ORC1-type DNA replication protein 2 {ECO:0000255|HAMAP-Rule:MF_01407};
GN Name=cdc6b; OrderedLocusNames=rrnB0004;
OS Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS B-1809) (Halobacterium marismortui).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Haloarcula.
OX NCBI_TaxID=272569;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX PubMed=15520287; DOI=10.1101/gr.2700304;
RA Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA Hood L., Ng W.V.;
RT "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT Dead Sea.";
RL Genome Res. 14:2221-2234(2004).
CC -!- FUNCTION: Involved in regulation of DNA replication.
CC {ECO:0000255|HAMAP-Rule:MF_01407}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC Rule:MF_01407}.
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DR EMBL; AY596298; AAV48219.1; -; Genomic_DNA.
DR RefSeq; WP_004966666.1; NZ_CP039136.1.
DR AlphaFoldDB; Q5UWY4; -.
DR SMR; Q5UWY4; -.
DR STRING; 272569.rrnB0004; -.
DR EnsemblBacteria; AAV48219; AAV48219; rrnB0004.
DR GeneID; 40150977; -.
DR GeneID; 64825111; -.
DR KEGG; hma:rrnB0004; -.
DR PATRIC; fig|272569.17.peg.4055; -.
DR eggNOG; arCOG00467; Archaea.
DR HOGENOM; CLU_025112_3_1_2; -.
DR OMA; QPIINGE; -.
DR Proteomes; UP000001169; Chromosome II.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd08768; Cdc6_C; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR015163; Cdc6_C.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF09079; Cdc6_C; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01074; Cdc6_C; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR02928; TIGR02928; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT CHAIN 1..412
FT /note="ORC1-type DNA replication protein 2"
FT /id="PRO_0000150989"
FT BINDING 61..65
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT BINDING 207
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT BINDING 219
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ SEQUENCE 412 AA; 46477 MW; 028343ADABB83BE5 CRC64;
MGPRFQPDDT LYKRRNTLKV EYVPDDIVGR DNEIEEYEAA LQPIINGEYP DNIFIYGKTG
VGKTAVTNFL LNELRESADH FEVDLTVISL NCDGLSTSYQ AAISLVNNLR GHENHIAETG
HPQSKVYRLL WNELNKLSGS VIIVLDEIDH ITDDTFLYQI TRADNNGYID NIQLGVIGIS
NDSTFREQLD AKVQSSLCET EISFPPYGTE ELQKVLEQRA EIAFHESALE DGVIPLCAAL
GRQDGGDARR AITLLRKAGD LARTENANSV TTDHVERAQE KLEAQQSMDI MRDLTEHEQL
TLYALTTLAA EGETPARSRI VYQRYKELCE FQGREPRTAR RMRSFLSDFE ILNLTLSEME
HRGQDGGTYR QHELNRDIAT VVDALQTIIG EFGAHQSIIE YLPDSGEEFA TM
