ID   CDC6D_HALMA             Reviewed;         524 AA.
AC   Q5UZ24;
DT   29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=ORC1-type DNA replication protein 4 {ECO:0000255|HAMAP-Rule:MF_01407};
GN   Name=cdc6d; OrderedLocusNames=rrnAC2711;
OS   Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS   B-1809) (Halobacterium marismortui).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=272569;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX   PubMed=15520287; DOI=10.1101/gr.2700304;
RA   Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA   Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA   Hood L., Ng W.V.;
RT   "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT   Dead Sea.";
RL   Genome Res. 14:2221-2234(2004).
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000255|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01407}.
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DR   EMBL; AY596297; AAV47479.1; -; Genomic_DNA.
DR   RefSeq; WP_011224383.1; NZ_CP039138.1.
DR   AlphaFoldDB; Q5UZ24; -.
DR   SMR; Q5UZ24; -.
DR   STRING; 272569.rrnAC2711; -.
DR   EnsemblBacteria; AAV47479; AAV47479; rrnAC2711.
DR   GeneID; 40153573; -.
DR   KEGG; hma:rrnAC2711; -.
DR   PATRIC; fig|272569.17.peg.3294; -.
DR   eggNOG; arCOG00467; Archaea.
DR   HOGENOM; CLU_025112_3_1_2; -.
DR   OMA; DMLGIIN; -.
DR   Proteomes; UP000001169; Chromosome I.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd08768; Cdc6_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02928; TIGR02928; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..524
FT                   /note="ORC1-type DNA replication protein 4"
FT                   /id="PRO_0000150987"
FT   REGION          1..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..41
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         128..132
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         325
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         337
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   524 AA;  58168 MW;  0726F2BC3E573949 CRC64;
     MTDKSNNPAP ASDPSTTETS NDADGSDGQL DAETDPGTST GPSDLDDVIL DNLDAGSDDP
     SDEASRGLFD DLLEGEPIFE NKEVLRPSYT PHKLPHREEQ INNMATILVT ALRGDTPSNI
     LIYGKTGTGK TASAKFVSEE LETTSQKYEV PCEVEYINCE VTDTQYRVLA QLANKFIDKN
     AQLIDDRIAE LEELQSQARE NTAALEETAF GSLDDVEAEI ESLEADKSEF EEVPMTGWPT
     DRVYSSFFDA VDYHERVVVI MLDEIDKLVE KSGDDTLYNL SRMNSELENS RVSIMGISND
     LKFTDFLDPR VKSSLGEEEI VFPPYDANQL RDILQARSDV AFKGDALTED VIPLCAAFAA
     QEHGDARRAL DLLRTAGELA ERDQTDNVLE DHVRQAQEKI ELDRVVEVVR TLPTQSKIVL
     FAIILLEKNG VHNINTGEVF NIYKNLCEEI DADILTQRRV TDLISELDML GIVNAVVVSK
     GRYGRTKEIS LSVPTEETEA VLLSDSRLGD IDDVQPFVQA RFDN