ID   CDC6H_HALMA             Reviewed;         442 AA.
AC   Q5V2P8;
DT   29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=ORC1-type DNA replication protein 8 {ECO:0000255|HAMAP-Rule:MF_01407};
GN   Name=cdc6h; OrderedLocusNames=rrnAC1262;
OS   Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS   B-1809) (Halobacterium marismortui).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=272569;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX   PubMed=15520287; DOI=10.1101/gr.2700304;
RA   Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA   Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA   Hood L., Ng W.V.;
RT   "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT   Dead Sea.";
RL   Genome Res. 14:2221-2234(2004).
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000255|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01407}.
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DR   EMBL; AY596297; AAV46204.1; -; Genomic_DNA.
DR   RefSeq; WP_004956661.1; NZ_CP039138.1.
DR   AlphaFoldDB; Q5V2P8; -.
DR   SMR; Q5V2P8; -.
DR   STRING; 272569.rrnAC1262; -.
DR   EnsemblBacteria; AAV46204; AAV46204; rrnAC1262.
DR   GeneID; 40152249; -.
DR   GeneID; 64822124; -.
DR   KEGG; hma:rrnAC1262; -.
DR   PATRIC; fig|272569.17.peg.1971; -.
DR   eggNOG; arCOG00467; Archaea.
DR   HOGENOM; CLU_025112_3_1_2; -.
DR   OMA; ARNDFLY; -.
DR   Proteomes; UP000001169; Chromosome I.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd08768; Cdc6_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF13401; AAA_22; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02928; TIGR02928; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..442
FT                   /note="ORC1-type DNA replication protein 8"
FT                   /id="PRO_0000150985"
FT   BINDING         66..70
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         218
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   442 AA;  49816 MW;  216A74824687708A CRC64;
     MVDVNENPFD GTDSIFERKQ PLKKDTFTPD TIFHRDEEIE FYINALQDVI VGHDPNNVFV
     YGPTGVGKTA VTKWVRDKLE EKAEAEDIPL TVVGPINCRN YRSAYALVNT LVNEFRDPEN
     QLPESGYSTD SVFEFLYEEI EAVGGNVLII LDEIDNIPAD ARNDFLYELP RAEANENTPI
     TDAKVGLIGI SNDLKFVDVL EPKVKSTLGE REIKFGPYDA TELRDILGYY ADIAFREDVL
     GEDVVPLAAA FSAQERGDVR QGLRILEKAG EYARMEGAEG VTEAHTRRAT DTIETDELLD
     YFEHDLSSQQ ALTYLATTLA LIEPKHEAST KRIYNLYSSI AESSGRRVKS ERKIYEFLDQ
     LSMQGLVRSA ERNLGRKGGR KYIYEVTDDP TDIINAALQS SYSDAVPSNV NGILEHYLED
     EATEFEAPDT TDDEQQNLWQ FT