CDC6M_HALMA
ID CDC6M_HALMA Reviewed; 422 AA.
AC Q5V7B0;
DT 29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 07-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=ORC1-type DNA replication protein 13 {ECO:0000255|HAMAP-Rule:MF_01407};
GN Name=cdc6m; OrderedLocusNames=pNG6174;
OS Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS B-1809) (Halobacterium marismortui).
OG Plasmid pNG600.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Haloarcula.
OX NCBI_TaxID=272569;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX PubMed=15520287; DOI=10.1101/gr.2700304;
RA Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA Hood L., Ng W.V.;
RT "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT Dead Sea.";
RL Genome Res. 14:2221-2234(2004).
CC -!- FUNCTION: Involved in regulation of DNA replication.
CC {ECO:0000255|HAMAP-Rule:MF_01407}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC Rule:MF_01407}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY596295; AAV44710.1; -; Genomic_DNA.
DR RefSeq; WP_011222485.1; NZ_CP039134.1.
DR AlphaFoldDB; Q5V7B0; -.
DR SMR; Q5V7B0; -.
DR PRIDE; Q5V7B0; -.
DR EnsemblBacteria; AAV44710; AAV44710; pNG6174.
DR GeneID; 40150729; -.
DR KEGG; hma:pNG6174; -.
DR PATRIC; fig|272569.17.peg.447; -.
DR HOGENOM; CLU_025112_2_1_2; -.
DR OMA; IFEKPWL; -.
DR Proteomes; UP000001169; Plasmid pNG600.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd08768; Cdc6_C; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR015163; Cdc6_C.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF09079; Cdc6_C; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01074; Cdc6_C; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR02928; TIGR02928; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA replication; Nucleotide-binding; Plasmid;
KW Reference proteome.
FT CHAIN 1..422
FT /note="ORC1-type DNA replication protein 13"
FT /id="PRO_0000150994"
FT BINDING 80..84
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT BINDING 231
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT BINDING 243
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ SEQUENCE 422 AA; 47740 MW; 6ADB85564A699D80 CRC64;
MPNNESTQTT VDEILNVDED NDEDESNIFE KPWLLEIDNV PDANRIVGRD DHITFLAKNL
RKMRTNSVPD NVLEWGETGT GKTLVARHVC ERLEAATEGT DSPIVTAYIN PDPISTYTST
FRKIAEQVNA KAENPLEVPY QGLSAEHYRD QKLWPVVQRE FSGGLVVIID EIDKHGEVNE
VLYTLSRTQS KDDVDFPVIT IGISNDIEFK GEIESRVQST LQPEHRTFTP YEEDQLIAIL
ENRRDAFYDG VLDDEVIPTT AELAAEEHGD ARRAVRLFRN AGEIADEEGD DIVTAEHVHE
ADELVEVELF MEMVKGTPLS GKLLLFALTR LDRNNPEKEW FRTSEIHEVY QTVARDVKVE
PKGYNRALEL LNKHVTTGVL ESKKKEGGDQ GKFRSYSLQG DVESTRTGLI NSTPELQTLM
GW
