ID   CDC6Z_METTF             Reviewed;         364 AA.
AC   P29570;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=ORC1-type DNA replication protein {ECO:0000255|HAMAP-Rule:MF_01407};
GN   Name=cdc6;
OS   Methanothermobacter thermautotrophicus (Methanobacterium thermoformicicum).
OG   Plasmid pFZ1.
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=145262;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DSM 3720 / Z-245;
RX   PubMed=1336177; DOI=10.1093/nar/20.24.6501;
RA   Noelling J., van Eeden F.J.M., Eggen R.I.L., de Vos W.M.;
RT   "Modular organization of related Archaeal plasmids encoding different
RT   restriction-modification systems in Methanobacterium thermoformicicum.";
RL   Nucleic Acids Res. 20:6501-6507(1992).
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000255|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01407}.
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DR   EMBL; X68367; CAA48438.1; -; Genomic_DNA.
DR   PIR; S30324; S26458.
DR   RefSeq; NP_039767.1; NC_001337.1.
DR   RefSeq; WP_010889853.1; NC_001337.1.
DR   AlphaFoldDB; P29570; -.
DR   SMR; P29570; -.
DR   GeneID; 24855020; -.
DR   PRO; PR:P29570; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02928; TIGR02928; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Plasmid.
FT   CHAIN           1..364
FT                   /note="ORC1-type DNA replication protein"
FT                   /id="PRO_0000151006"
FT   BINDING         58..62
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         184
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         196
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   364 AA;  40662 MW;  48352B8BDE7877A7 CRC64;
     MFEKRPKLFK NRDVLSPLFV PDTLQDRKEE VGAISQYLGY ILDGATPPHL LIVGPPGSGK
     TVTTKYVINE LEKHTSDAVI EYIVADGTAY QVATSIARAP RRGLGFLNIV EKIRERASEG
     KMIIVMDEID KTLSRDGDKL LYHLSREPNV CIVGLSNKLT VMDMIGDSGV ISSFKPRRIS
     FAPYSAPQLE EILNYRVEMA FNDGVLEDDV VPLCAALAAQ RNGDARYALD LLSFAADIAI
     RQLKGVVSES DVRMATDEVE VEFIRRSIEQ LRDNQKILLY AVMTSQGGTP TEIYRKYNKM
     AEEQFGGNAL TQRRLSQLLR ELELYGLVEI EVVGRGRGRG VNWHVVPSSS IDPDLMLEAI
     RRSL