ID   CDC6_DESA1              Reviewed;         394 AA.
AC   B8D6H2;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=ORC1-type DNA replication protein {ECO:0000255|HAMAP-Rule:MF_01407};
GN   Name=cdc6; OrderedLocusNames=DKAM_1377;
OS   Desulfurococcus amylolyticus (strain DSM 18924 / JCM 16383 / VKM B-2413 /
OS   1221n) (Desulfurococcus kamchatkensis).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Desulfurococcus.
OX   NCBI_TaxID=490899;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18924 / JCM 16383 / VKM B-2413 / 1221n;
RX   PubMed=19114480; DOI=10.1128/jb.01525-08;
RA   Ravin N.V., Mardanov A.V., Beletsky A.V., Kublanov I.V., Kolganova T.V.,
RA   Lebedinsky A.V., Chernyh N.A., Bonch-Osmolovskaya E.A., Skryabin K.G.;
RT   "Complete genome sequence of the anaerobic, protein-degrading
RT   hyperthermophilic crenarchaeon Desulfurococcus kamchatkensis.";
RL   J. Bacteriol. 191:2371-2379(2009).
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000255|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01407}.
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DR   EMBL; CP001140; ACL11703.1; -; Genomic_DNA.
DR   RefSeq; WP_012609044.1; NC_011766.1.
DR   AlphaFoldDB; B8D6H2; -.
DR   SMR; B8D6H2; -.
DR   STRING; 490899.DKAM_1377; -.
DR   PRIDE; B8D6H2; -.
DR   EnsemblBacteria; ACL11703; ACL11703; DKAM_1377.
DR   GeneID; 7171419; -.
DR   KEGG; dka:DKAM_1377; -.
DR   eggNOG; arCOG00467; Archaea.
DR   HOGENOM; CLU_025112_3_1_2; -.
DR   OMA; DMLGIIN; -.
DR   Proteomes; UP000006903; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd08768; Cdc6_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF13401; AAA_22; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02928; TIGR02928; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..394
FT                   /note="ORC1-type DNA replication protein"
FT                   /id="PRO_1000184586"
FT   BINDING         68..72
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         212
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         224
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   394 AA;  44774 MW;  21AE931FB843C2DC CRC64;
     MADIIDELIR KRGFASRIFR NREVLHPDYI PDTLPHRENE IRRLAEHLLV SAQGMRPSNV
     LIYGLTGTGK TVVVKYVVSK LKEKASSLNK RLDYAYVNTR KLDTTYRVIA SIAQSIGLRV
     PHTGLAISEV YRRYINALDS WGGLHIIVLD EVDYYVKREG DDLIYKLVRA NEELSKAKIV
     LIGITNDVNF VENLDPRVRS SMGEIEMVFP PYNAEQLFTI LKQRAELAFN QGVIEDGVIS
     YCSALAAREH GDARRALDLL RVSGEIAERE GAERVTIEYV KKATLEIEEG RIYQSVVTLP
     LHQKLVLKKI VELVEAKEST TTGEVYTAYS NIMRNLKYEP LSLRRISEII SQLDMMGLII
     SEVVNRGKYG ITRIIKIRKD MLPVIKDALK DVEA