ID   CDC6_METB6              Reviewed;         430 AA.
AC   A7I464;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=ORC1-type DNA replication protein {ECO:0000255|HAMAP-Rule:MF_01407};
GN   Name=cdc6; OrderedLocusNames=Mboo_0001;
OS   Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanoregulaceae; Methanoregula.
OX   NCBI_TaxID=456442;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21154 / JCM 14090 / 6A8;
RX   PubMed=25998264; DOI=10.1099/mic.0.000117;
RA   Braeuer S., Cadillo-Quiroz H., Kyrpides N., Woyke T., Goodwin L.,
RA   Detter C., Podell S., Yavitt J.B., Zinder S.H.;
RT   "Genome of Methanoregula boonei 6A8 reveals adaptations to oligotrophic
RT   peatland environments.";
RL   Microbiology 161:1572-1581(2015).
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000255|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01407}.
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DR   EMBL; CP000780; ABS54525.1; -; Genomic_DNA.
DR   RefSeq; WP_011991013.1; NC_009712.1.
DR   AlphaFoldDB; A7I464; -.
DR   SMR; A7I464; -.
DR   STRING; 456442.Mboo_0001; -.
DR   EnsemblBacteria; ABS54525; ABS54525; Mboo_0001.
DR   GeneID; 5411407; -.
DR   KEGG; mbn:Mboo_0001; -.
DR   eggNOG; arCOG00467; Archaea.
DR   HOGENOM; CLU_025112_3_1_2; -.
DR   OMA; DMLGIIN; -.
DR   OrthoDB; 58376at2157; -.
DR   Proteomes; UP000002408; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd08768; Cdc6_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF13401; AAA_22; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02928; TIGR02928; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..430
FT                   /note="ORC1-type DNA replication protein"
FT                   /id="PRO_1000068438"
FT   BINDING         71..75
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         226
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         238
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   430 AA;  48096 MW;  09A796EA242D7E3B CRC64;
     MPETEDPATG LFIKYLSNNR IFRDREVLRH SYRPQILPHR QPQIDTIASI LAPSLRNETP
     SNILIYGKTG TGKTASVRYV GSELEKASST MGTTCRIVHL NCEVIDTQYR VLAQIAKCID
     DVDEASSDKA KIHIPMTGWP TDQVYSELKN QLDTGGGVLV IVLDEIDKLV KKSGDDTLYN
     LTRINSDLKN SKVSIIGISN DLSFKDFLDP RVLSSLSEEE IVFPPYNAPQ LVDILTQRAA
     GAFLDGAIAD GVIPLCSALA AQEHGDARRA LDLLRISGEL ADRDESKQVT DVHVKQAQAK
     IETDSMIECI ATLPTQSKLI LFSMLTLEQL GQNIFTSGEV SRVYQDIAPE IQLDILTHRR
     ITDLISELNM LGVINTRVVS RGRYGRTKEM WFDANTGKIR EVVLKDPRLN GLKDLDINQM
     ETKWLKTWFR