ID   CDC6_METHJ              Reviewed;         424 AA.
AC   Q2FN79;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=ORC1-type DNA replication protein {ECO:0000255|HAMAP-Rule:MF_01407};
GN   Name=cdc6; OrderedLocusNames=Mhun_2471;
OS   Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS   JF-1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX   NCBI_TaxID=323259;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1;
RX   PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA   Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA   Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA   Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT   "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL   Stand. Genomic Sci. 11:2-2(2016).
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000255|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01407}.
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DR   EMBL; CP000254; ABD42171.1; -; Genomic_DNA.
DR   RefSeq; WP_011449429.1; NC_007796.1.
DR   AlphaFoldDB; Q2FN79; -.
DR   SMR; Q2FN79; -.
DR   STRING; 323259.Mhun_2471; -.
DR   PRIDE; Q2FN79; -.
DR   EnsemblBacteria; ABD42171; ABD42171; Mhun_2471.
DR   GeneID; 3923976; -.
DR   KEGG; mhu:Mhun_2471; -.
DR   eggNOG; arCOG00467; Archaea.
DR   HOGENOM; CLU_025112_3_1_2; -.
DR   OMA; DMLGIIN; -.
DR   OrthoDB; 58376at2157; -.
DR   Proteomes; UP000001941; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd08768; Cdc6_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF13401; AAA_22; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02928; TIGR02928; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..424
FT                   /note="ORC1-type DNA replication protein"
FT                   /id="PRO_0000307416"
FT   BINDING         71..75
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         226
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         238
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   424 AA;  47966 MW;  6F51847C58226BCD CRC64;
     MTQDMNDSPG LFDKYLSENR IFRDREVLRH SYRPHILPHR KPQIDQIAAI LAPALQTETP
     SNILIYGKTG TGKTASVRYV GSELESVSAR RGTVCRVIHL NCEVIDTQYR VLAQISKLIM
     GEDETPSDKI KTHIPMTGWP TDQVYSELKN QIELNSGVFI IILDEIDKLV KKSGDDTLYN
     LTRINTDLNR SKVSIIGISN DLGFKTFLDP RVLSSLSEEE LVFPPYNAPQ LCDILQQRAV
     IGFAEDALED EVIPLCAALA AQEHGDARRA LDLLRISGEL ADRENGSKVT VEHVKKAQAK
     IETDSMVECI RTLPTQSKIV LYCMLLLHRA GQRIFISGDV TRIYKELTPF LEIDVLTARR
     ISDLISELNM LGVINTRLVN RGRHGRTKEM WFDTNTDKIW EVIMEESDGR LAQVDEQIVV
     QILR