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CDC6_METMJ
ID   CDC6_METMJ              Reviewed;         427 AA.
AC   A3CRD6;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=ORC1-type DNA replication protein {ECO:0000255|HAMAP-Rule:MF_01407};
GN   Name=cdc6; OrderedLocusNames=Memar_0001;
OS   Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanomicrobiaceae; Methanoculleus.
OX   NCBI_TaxID=368407;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35101 / DSM 1498 / JR1;
RX   PubMed=21304656; DOI=10.4056/sigs.32535;
RA   Anderson I.J., Sieprawska-Lupa M., Lapidus A., Nolan M., Copeland A.,
RA   Glavina Del Rio T., Tice H., Dalin E., Barry K., Saunders E., Han C.,
RA   Brettin T., Detter J.C., Bruce D., Mikhailova N., Pitluck S., Hauser L.,
RA   Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT   "Complete genome sequence of Methanoculleus marisnigri Romesser et al. 1981
RT   type strain JR1.";
RL   Stand. Genomic Sci. 1:189-196(2009).
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000255|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01407}.
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DR   EMBL; CP000562; ABN55936.1; -; Genomic_DNA.
DR   RefSeq; WP_011842857.1; NC_009051.1.
DR   AlphaFoldDB; A3CRD6; -.
DR   SMR; A3CRD6; -.
DR   STRING; 368407.Memar_0001; -.
DR   EnsemblBacteria; ABN55936; ABN55936; Memar_0001.
DR   GeneID; 4848380; -.
DR   KEGG; mem:Memar_0001; -.
DR   eggNOG; arCOG00467; Archaea.
DR   HOGENOM; CLU_025112_3_1_2; -.
DR   OMA; DMLGIIN; -.
DR   OrthoDB; 58376at2157; -.
DR   Proteomes; UP000002146; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd08768; Cdc6_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF13401; AAA_22; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02928; TIGR02928; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding.
FT   CHAIN           1..427
FT                   /note="ORC1-type DNA replication protein"
FT                   /id="PRO_0000307415"
FT   BINDING         71..75
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         226
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         238
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   427 AA;  48091 MW;  B9D0001DB7A25009 CRC64;
     MSDDKTSPMG LFKKYLTNRR IFKNREVLRH NYRPQILPHR KPQIDEIASI LAPALTNETP
     SNILIYGKTG TGKTASVRYV GTELENASAL AGTKCKIVHL NCEVIDTQYR VLAQIANGLD
     NADEHPSDST RSHIPMTGWP TDQVYMELKN QLESSGGVMV IILDEIDKLV KKSGDDTLYN
     LTRINSDLKF AKVSIIGISN DLRFTDFLDP RVLSSLSEEE IVFPPYNAPQ LCDILQQRAE
     MAFVEGALDE TVIPLCAALA AQEHGDARRA LDLLRVSGEL ADRENASGVA EKHVRMAQEK
     IETDSMVECI STLPTQSKAV LYAMLILEQM GKRIFTSGEV TVVYREIARI IDLDVLTHRR
     ITDLISELNM LGVINTRVIS RGRYGRTKEM WFDAATSKIE EVVTRDPRLD DERLKKLDVN
     RLRAMFR
 
 
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