CDC6_METMJ
ID CDC6_METMJ Reviewed; 427 AA.
AC A3CRD6;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=ORC1-type DNA replication protein {ECO:0000255|HAMAP-Rule:MF_01407};
GN Name=cdc6; OrderedLocusNames=Memar_0001;
OS Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanomicrobiaceae; Methanoculleus.
OX NCBI_TaxID=368407;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35101 / DSM 1498 / JR1;
RX PubMed=21304656; DOI=10.4056/sigs.32535;
RA Anderson I.J., Sieprawska-Lupa M., Lapidus A., Nolan M., Copeland A.,
RA Glavina Del Rio T., Tice H., Dalin E., Barry K., Saunders E., Han C.,
RA Brettin T., Detter J.C., Bruce D., Mikhailova N., Pitluck S., Hauser L.,
RA Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT "Complete genome sequence of Methanoculleus marisnigri Romesser et al. 1981
RT type strain JR1.";
RL Stand. Genomic Sci. 1:189-196(2009).
CC -!- FUNCTION: Involved in regulation of DNA replication.
CC {ECO:0000255|HAMAP-Rule:MF_01407}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC Rule:MF_01407}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000562; ABN55936.1; -; Genomic_DNA.
DR RefSeq; WP_011842857.1; NC_009051.1.
DR AlphaFoldDB; A3CRD6; -.
DR SMR; A3CRD6; -.
DR STRING; 368407.Memar_0001; -.
DR EnsemblBacteria; ABN55936; ABN55936; Memar_0001.
DR GeneID; 4848380; -.
DR KEGG; mem:Memar_0001; -.
DR eggNOG; arCOG00467; Archaea.
DR HOGENOM; CLU_025112_3_1_2; -.
DR OMA; DMLGIIN; -.
DR OrthoDB; 58376at2157; -.
DR Proteomes; UP000002146; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd08768; Cdc6_C; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR015163; Cdc6_C.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF09079; Cdc6_C; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01074; Cdc6_C; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR02928; TIGR02928; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA replication; Nucleotide-binding.
FT CHAIN 1..427
FT /note="ORC1-type DNA replication protein"
FT /id="PRO_0000307415"
FT BINDING 71..75
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT BINDING 226
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT BINDING 238
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ SEQUENCE 427 AA; 48091 MW; B9D0001DB7A25009 CRC64;
MSDDKTSPMG LFKKYLTNRR IFKNREVLRH NYRPQILPHR KPQIDEIASI LAPALTNETP
SNILIYGKTG TGKTASVRYV GTELENASAL AGTKCKIVHL NCEVIDTQYR VLAQIANGLD
NADEHPSDST RSHIPMTGWP TDQVYMELKN QLESSGGVMV IILDEIDKLV KKSGDDTLYN
LTRINSDLKF AKVSIIGISN DLRFTDFLDP RVLSSLSEEE IVFPPYNAPQ LCDILQQRAE
MAFVEGALDE TVIPLCAALA AQEHGDARRA LDLLRVSGEL ADRENASGVA EKHVRMAQEK
IETDSMVECI STLPTQSKAV LYAMLILEQM GKRIFTSGEV TVVYREIARI IDLDVLTHRR
ITDLISELNM LGVINTRVIS RGRYGRTKEM WFDAATSKIE EVVTRDPRLD DERLKKLDVN
RLRAMFR