ID   CDC6_THEKO              Reviewed;         415 AA.
AC   Q5JET2;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=ORC1-type DNA replication protein {ECO:0000255|HAMAP-Rule:MF_01407};
GN   Name=cdc6; OrderedLocusNames=TK1901;
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1;
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000255|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01407}.
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DR   EMBL; AP006878; BAD86090.1; -; Genomic_DNA.
DR   RefSeq; WP_011250852.1; NC_006624.1.
DR   AlphaFoldDB; Q5JET2; -.
DR   SMR; Q5JET2; -.
DR   STRING; 69014.TK1901; -.
DR   EnsemblBacteria; BAD86090; BAD86090; TK1901.
DR   GeneID; 3233962; -.
DR   KEGG; tko:TK1901; -.
DR   PATRIC; fig|69014.16.peg.1859; -.
DR   eggNOG; arCOG00467; Archaea.
DR   HOGENOM; CLU_025112_3_1_2; -.
DR   InParanoid; Q5JET2; -.
DR   OMA; DMLGIIN; -.
DR   OrthoDB; 58376at2157; -.
DR   PhylomeDB; Q5JET2; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003688; F:DNA replication origin binding; IBA:GO_Central.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd08768; Cdc6_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02928; TIGR02928; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..415
FT                   /note="ORC1-type DNA replication protein"
FT                   /id="PRO_0000151014"
FT   BINDING         69..73
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         217
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         229
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   415 AA;  47636 MW;  E16DE5A8E3E01C2C CRC64;
     MDDDYLSSIF EKYLHARKIF KNKEVLRHSY TPKELPHRHK QIDDLAHILV PVLRGETPSN
     VFVYGKTGTG KTVTVKFVTE ELKKISQKYN IPVEVIYINC EIIDTHYRVL ARIVNHFKEE
     SGIEVPLVGW PTDEVYAKLK EVIDAKERFV IIVLDEIDKL IKKSGDDILY SLTRINSELS
     KAKVSIIGIS NDLKFKEYLD ARVLSSLSEE EVVFPPYDAN QLRDILMQRA KEAFYEGVLD
     DAVVPLCAAL AAREHGDARR ALDLLRVAGE IAEREGASKV TERHVWKAQE KIEQDTMEEV
     IKTLPLHSKV LLYAIVMLDE NGELPANTGE VYSIYKMLCD SLDVEPLTQR RVSDLINELD
     MLGIINAKVV SKGRYGRTKE IRLNVTPYMV KNIYRHDEQV RPLLTLSLSR QRRLF