ID   CDC6_THEON              Reviewed;         415 AA.
AC   B6YUE9;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-JAN-2009, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=ORC1-type DNA replication protein {ECO:0000255|HAMAP-Rule:MF_01407};
GN   Name=cdc6; OrderedLocusNames=TON_1644;
OS   Thermococcus onnurineus (strain NA1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=523850;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA1;
RX   PubMed=18790866; DOI=10.1128/jb.00746-08;
RA   Lee H.S., Kang S.G., Bae S.S., Lim J.K., Cho Y., Kim Y.J., Jeon J.H.,
RA   Cha S.-S., Kwon K.K., Kim H.-T., Park C.-J., Lee H.-W., Kim S.I., Chun J.,
RA   Colwell R.R., Kim S.-J., Lee J.-H.;
RT   "The complete genome sequence of Thermococcus onnurineus NA1 reveals a
RT   mixed heterotrophic and carboxydotrophic metabolism.";
RL   J. Bacteriol. 190:7491-7499(2008).
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000255|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01407}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000855; ACJ17134.1; -; Genomic_DNA.
DR   RefSeq; WP_012572606.1; NC_011529.1.
DR   AlphaFoldDB; B6YUE9; -.
DR   SMR; B6YUE9; -.
DR   STRING; 523850.TON_1644; -.
DR   PRIDE; B6YUE9; -.
DR   EnsemblBacteria; ACJ17134; ACJ17134; TON_1644.
DR   GeneID; 7018684; -.
DR   KEGG; ton:TON_1644; -.
DR   PATRIC; fig|523850.10.peg.1657; -.
DR   eggNOG; arCOG00467; Archaea.
DR   HOGENOM; CLU_025112_3_1_2; -.
DR   OMA; DMLGIIN; -.
DR   OrthoDB; 58376at2157; -.
DR   Proteomes; UP000002727; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd08768; Cdc6_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02928; TIGR02928; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding.
FT   CHAIN           1..415
FT                   /note="ORC1-type DNA replication protein"
FT                   /id="PRO_1000145508"
FT   BINDING         69..73
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         217
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         229
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   415 AA;  47541 MW;  399E11D16510AC75 CRC64;
     MDDNYLDSIF EKYLHAKKIF KNKEVLRHSY TPRELPHRRE QIENLAHILV PVLRGETPSN
     VFVYGKTGTG KTVTIKFVTE ELKKISQKYN VPVDVIYVNC EIVDTQYRVL ANIVNHFREE
     SGVEVPLVGW PTDEVYSKLK AVIDAKERFV IIVLDEIDKL IKKSGDDILY SLTRINTELH
     RAKVSIIGIS NDLKFKDYLD PRVLSSLSEE EVVFPPYDAN QLRDILMQRA KDAFNEGVLD
     DGVVPLCAAL AAREHGDARR ALDLLRVAGE IAEREGASKV TERHVWKAQE KIEQDTMEEV
     IKTLPLHSKV LLYAIVLLDE NGELPANTGD VYSVYKSLCD HIDLEPLTQR RVSDLINELD
     MLGIINAKVV SKGRYGRTKE IRLNVTPYKV KNIYRHDHQL QTVLTISMSR QRRLL