CDF4_ARATH
ID CDF4_ARATH Reviewed; 170 AA.
AC O22967; Q56YL4;
DT 09-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Cyclic dof factor 4;
DE AltName: Full=Dof zinc finger protein DOF2.3;
DE Short=AtDOF2.3;
GN Name=CDF4; Synonyms=DOF2.3; OrderedLocusNames=At2g34140;
GN ORFNames=T14G11.26;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12475498; DOI=10.1016/s1360-1385(02)02362-2;
RA Yanagisawa S.;
RT "The Dof family of plant transcription factors.";
RL Trends Plant Sci. 7:555-560(2002).
RN [6]
RP FUNCTION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=19619493; DOI=10.1016/j.devcel.2009.06.015;
RA Fornara F., Panigrahi K.C., Gissot L., Sauerbrunn N., Ruehl M.,
RA Jarillo J.A., Coupland G.;
RT "Arabidopsis DOF transcription factors act redundantly to reduce CONSTANS
RT expression and are essential for a photoperiodic flowering response.";
RL Dev. Cell 17:75-86(2009).
CC -!- FUNCTION: Transcription factor that binds specifically to a 5'-AA[AG]G-
CC 3' consensus core sequence (By similarity). Transcriptional repressor
CC of 'CONSTANS' expression (By similarity). Regulates a photoperiodic
CC flowering response. {ECO:0000250, ECO:0000269|PubMed:19619493}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in the vasculature of cotyledons and
CC hypocotyls, leaves and roots. {ECO:0000269|PubMed:19619493}.
CC -!- INDUCTION: Circadian-regulation. The transcript level rises
CC progressively from dawn and decreases during the night.
CC {ECO:0000269|PubMed:19619493}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC002341; AAB67632.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08923.1; -; Genomic_DNA.
DR EMBL; BT010496; AAQ65119.1; -; mRNA.
DR EMBL; AK221308; BAD94068.1; -; mRNA.
DR PIR; H84752; H84752.
DR RefSeq; NP_180961.1; NM_128965.5.
DR AlphaFoldDB; O22967; -.
DR BioGRID; 3322; 12.
DR IntAct; O22967; 11.
DR STRING; 3702.AT2G34140.1; -.
DR PaxDb; O22967; -.
DR PRIDE; O22967; -.
DR EnsemblPlants; AT2G34140.1; AT2G34140.1; AT2G34140.
DR GeneID; 817975; -.
DR Gramene; AT2G34140.1; AT2G34140.1; AT2G34140.
DR KEGG; ath:AT2G34140; -.
DR Araport; AT2G34140; -.
DR TAIR; locus:2055506; AT2G34140.
DR eggNOG; ENOG502RZI1; Eukaryota.
DR HOGENOM; CLU_078374_1_0_1; -.
DR InParanoid; O22967; -.
DR OMA; EDQWHLF; -.
DR OrthoDB; 1471866at2759; -.
DR PhylomeDB; O22967; -.
DR PRO; PR:O22967; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22967; baseline and differential.
DR Genevisible; O22967; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:1902455; P:negative regulation of stem cell population maintenance; IMP:TAIR.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:TAIR.
DR InterPro; IPR045174; Dof.
DR InterPro; IPR003851; Znf_Dof.
DR PANTHER; PTHR31089; PTHR31089; 1.
DR Pfam; PF02701; zf-Dof; 1.
DR PROSITE; PS01361; ZF_DOF_1; 1.
DR PROSITE; PS50884; ZF_DOF_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Flowering; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..170
FT /note="Cyclic dof factor 4"
FT /id="PRO_0000074274"
FT ZN_FING 58..112
FT /note="Dof-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT REGION 25..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 60
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT BINDING 63
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT BINDING 85
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT BINDING 88
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
SQ SEQUENCE 170 AA; 18927 MW; 3F396ACC137682E7 CRC64;
MATQDSQGIK LFGKTIAFNT RTIKNEEETH PPEQEATIAV RSSSSSDLTA EKRPDKIIAC
PRCKSMETKF CYFNNYNVNQ PRHFCKGCHR YWTAGGALRN VPVGAGRRKS KPPGRVVVGM
LGDGNGVRQV ELINGLLVEE WQHAAAAAHG SFRHDFPMKR LRCYSDGQSC
