CDF5_ARATH
ID CDF5_ARATH Reviewed; 399 AA.
AC Q9SEZ3; O81601; Q1H541;
DT 25-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Cyclic dof factor 5;
DE AltName: Full=Dof zinc finger protein DOF1.10;
DE Short=AtDOF1.10;
DE AltName: Full=H-protein promoter-binding factor 2b;
GN Name=CDF5; Synonyms=DOF1.10, HPPBF-2B; OrderedLocusNames=At1g69570;
GN ORFNames=F10D13.20, F24J1.25;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Abbaraju H.K.R., Oliver D.J.;
RT "Molecular cloning of the H-protein promoter binding factor-2b (HPPBF-2b)
RT from Arabidopsis.";
RL Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Shinn P., Chen H., Kim C.J., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12475498; DOI=10.1016/s1360-1385(02)02362-2;
RA Yanagisawa S.;
RT "The Dof family of plant transcription factors.";
RL Trends Plant Sci. 7:555-560(2002).
RN [7]
RP FUNCTION, INDUCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=19619493; DOI=10.1016/j.devcel.2009.06.015;
RA Fornara F., Panigrahi K.C., Gissot L., Sauerbrunn N., Ruehl M.,
RA Jarillo J.A., Coupland G.;
RT "Arabidopsis DOF transcription factors act redundantly to reduce CONSTANS
RT expression and are essential for a photoperiodic flowering response.";
RL Dev. Cell 17:75-86(2009).
CC -!- FUNCTION: Transcription factor that binds specifically to a 5'-AA[AG]G-
CC 3' consensus core sequence (By similarity). Regulates a photoperiodic
CC flowering response. Transcriptional repressor of 'CONSTANS' expression.
CC {ECO:0000250, ECO:0000269|PubMed:19619493}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- INDUCTION: Circadian-regulation. Highly expressed at the beginning of
CC the light period, then decreases, reaching a minimum between 16 and 29
CC hours after dawn before rising again at the end of the day.
CC {ECO:0000269|PubMed:19619493}.
CC -!- DISRUPTION PHENOTYPE: Early flowering. {ECO:0000269|PubMed:19619493}.
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DR EMBL; AF079504; AAC28391.1; -; mRNA.
DR EMBL; AC021046; AAF24604.1; -; Genomic_DNA.
DR EMBL; AC073178; AAG60104.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34950.1; -; Genomic_DNA.
DR EMBL; AK176346; BAD44109.1; -; mRNA.
DR EMBL; BT025623; ABF59041.1; -; mRNA.
DR PIR; D96717; D96717.
DR PIR; T51953; T51953.
DR RefSeq; NP_177116.1; NM_105626.4.
DR AlphaFoldDB; Q9SEZ3; -.
DR BioGRID; 28514; 13.
DR IntAct; Q9SEZ3; 13.
DR STRING; 3702.AT1G69570.1; -.
DR iPTMnet; Q9SEZ3; -.
DR PaxDb; Q9SEZ3; -.
DR PRIDE; Q9SEZ3; -.
DR ProteomicsDB; 222808; -.
DR EnsemblPlants; AT1G69570.1; AT1G69570.1; AT1G69570.
DR GeneID; 843293; -.
DR Gramene; AT1G69570.1; AT1G69570.1; AT1G69570.
DR KEGG; ath:AT1G69570; -.
DR Araport; AT1G69570; -.
DR TAIR; locus:2007151; AT1G69570.
DR eggNOG; ENOG502QSI8; Eukaryota.
DR HOGENOM; CLU_030533_1_1_1; -.
DR InParanoid; Q9SEZ3; -.
DR OMA; AMNFRES; -.
DR OrthoDB; 853832at2759; -.
DR PhylomeDB; Q9SEZ3; -.
DR PRO; PR:Q9SEZ3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SEZ3; baseline and differential.
DR Genevisible; Q9SEZ3; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:0048579; P:negative regulation of long-day photoperiodism, flowering; IMP:TAIR.
DR GO; GO:0048577; P:negative regulation of short-day photoperiodism, flowering; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:TAIR.
DR InterPro; IPR045174; Dof.
DR InterPro; IPR003851; Znf_Dof.
DR PANTHER; PTHR31089; PTHR31089; 1.
DR Pfam; PF02701; zf-Dof; 1.
DR PROSITE; PS01361; ZF_DOF_1; 1.
DR PROSITE; PS50884; ZF_DOF_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Flowering; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..399
FT /note="Cyclic dof factor 5"
FT /id="PRO_0000074271"
FT ZN_FING 132..186
FT /note="Dof-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT REGION 29..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 134
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT BINDING 137
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT BINDING 159
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT BINDING 162
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT CONFLICT 8..9
FT /note="EI -> VRH (in Ref. 1; AAC28391)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 399 AA; 44007 MW; 3D7D5014794523EA CRC64;
MSKSRDTEIK LFGRTITSLL DVNCYDPSSL SPVHDVSSDP SKEDSSSSSS SCSPTIGPIR
VPVKKSEQES NKFKDPYILS DLNEPPKAVS EISSPRSSKN NCDQQSEITT TTTTSTTSGE
KSTALKKPDK LIPCPRCESA NTKFCYYNNY NVNQPRYFCR NCQRYWTAGG SMRNVPVGSG
RRKNKGWPSS NHYLQVTSED CDNNNSGTIL SFGSSESSVT ETGKHQSGDT AKISADSVSQ
ENKSYQGFLP PQVMLPNNSS PWPYQWSPTG PNASFYPVPF YWGCTVPIYP TSETSSCLGK
RSRDQTEGRI NDTNTTITTT RARLVSESLR MNIEASKSAV WSKLPTKPEK KTQGFSLFNG
FDTKGNSNRS SLVSETSHSL QANPAAMSRA MNFRESMQQ