ID   CDIB_YERPE              Reviewed;         562 AA.
AC   Q7CGD8; Q74RU9;
DT   04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Outer membrane transporter CdiB {ECO:0000305};
GN   Name=cdib {ECO:0000303|PubMed:21085179}; Synonyms=fhaC3;
GN   OrderedLocusNames=y3580, YP_2918, YPO0598; ORFNames=DJ56_3412;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15262951; DOI=10.1128/jb.186.15.5147-5152.2004;
RA   Zhou D., Tong Z., Song Y., Han Y., Pei D., Pang X., Zhai J., Li M., Cui B.,
RA   Qi Z., Jin L., Dai R., Du Z., Wang J., Guo Z., Wang J., Huang P., Yang R.;
RT   "Genetics of metabolic variations between Yersinia pestis biovars and the
RT   proposal of a new biovar, microtus.";
RL   J. Bacteriol. 186:5147-5152(2004).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Colorado 92;
RA   Bishop-Lilly K.A., Broomall S.M., Chain P.S., Chertkov O., Coyne S.R.,
RA   Daligault H.E., Davenport K.W., Erkkila T., Frey K.G., Gibbons H.S., Gu W.,
RA   Jaissle J., Johnson S.L., Koroleva G.I., Ladner J.T., Lo C.-C.,
RA   Minogue T.D., Munk C., Palacios G.F., Redden C.L., Rosenzweig C.N.,
RA   Scholz M.B., Teshima H., Xu Y.;
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN   [6]
RP   FUNCTION.
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=21085179; DOI=10.1038/nature09490;
RA   Aoki S.K., Diner E.J., de Roodenbeke C.T., Burgess B.R., Poole S.J.,
RA   Braaten B.A., Jones A.M., Webb J.S., Hayes C.S., Cotter P.A., Low D.A.;
RT   "A widespread family of polymorphic contact-dependent toxin delivery
RT   systems in bacteria.";
RL   Nature 468:439-442(2010).
CC   -!- FUNCTION: Potential outer membrane protein component of a toxin-
CC       immunity protein module, which functions as a cellular contact-
CC       dependent growth inhibition (CDI) system. CDI modules allow bacteria to
CC       communicate with and inhibit the growth of closely related neighboring
CC       bacteria in a contact-dependent fashion. This protein may be required
CC       for secretion and assembly of the CdiA toxin protein.
CC       {ECO:0000305|PubMed:21085179}.
CC   -!- FUNCTION: Probable member of a two partner secretion pathway (TPS) in
CC       which it mediates the secretion of CdiA. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane
CC       {ECO:0000305|PubMed:21085179}.
CC   -!- SIMILARITY: Belongs to the TPS (TC 1.B.20) family. {ECO:0000305}.
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DR   EMBL; AE009952; AAM87128.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS63099.1; -; Genomic_DNA.
DR   EMBL; AL590842; CAL19278.1; -; Genomic_DNA.
DR   EMBL; JPMB01000007; KGA55190.1; -; Genomic_DNA.
DR   PIR; AD0074; AD0074.
DR   RefSeq; WP_002210394.1; NZ_WUCM01000076.1.
DR   RefSeq; YP_002345670.1; NC_003143.1.
DR   AlphaFoldDB; Q7CGD8; -.
DR   SMR; Q7CGD8; -.
DR   STRING; 214092.YPO0598; -.
DR   TCDB; 1.B.20.1.11; the two-partner secretion (tps) family.
DR   PaxDb; Q7CGD8; -.
DR   DNASU; 1148527; -.
DR   EnsemblBacteria; AAM87128; AAM87128; y3580.
DR   EnsemblBacteria; AAS63099; AAS63099; YP_2918.
DR   GeneID; 57974019; -.
DR   KEGG; ype:YPO0598; -.
DR   KEGG; ypk:y3580; -.
DR   KEGG; ypm:YP_2918; -.
DR   PATRIC; fig|214092.21.peg.854; -.
DR   eggNOG; COG2831; Bacteria.
DR   HOGENOM; CLU_020581_2_0_6; -.
DR   OMA; HWLPLQR; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0098046; C:type V protein secretion system complex; IBA:GO_Central.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0046819; P:protein secretion by the type V secretion system; IBA:GO_Central.
DR   InterPro; IPR005565; Hemolysn_activator_HlyB_C.
DR   InterPro; IPR013686; Polypept-transport_assoc_ShlB.
DR   InterPro; IPR034746; POTRA.
DR   InterPro; IPR035251; ShlB_POTRA.
DR   InterPro; IPR027282; TPS.
DR   Pfam; PF08479; POTRA_2; 1.
DR   Pfam; PF17287; POTRA_3; 1.
DR   Pfam; PF03865; ShlB; 1.
DR   PIRSF; PIRSF029745; FhaC; 1.
DR   PROSITE; PS51779; POTRA; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane beta strand; Transport.
FT   CHAIN           1..562
FT                   /note="Outer membrane transporter CdiB"
FT                   /id="PRO_0000432085"
FT   DOMAIN          77..153
FT                   /note="POTRA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
SQ   SEQUENCE   562 AA;  62637 MW;  022EBFDD565D5DC7 CRC64;
     MSRFYYSILV AGVLLKIVAI PDASYGAELA PVQQSIHQQE RQRALEERLA PPTPDVRLSA
     PSAFFSRIIF PLETPCFVIN RIKISGAEPL PRWLPLQRIA DQAQGQCLGA KGINLLMSQM
     QNRLVDHGYV TTRVLAPQQD LNSGTLALNV VPGKIRGVEL TPDSNRYVTL FSAFPARAGT
     LLDLRDIEQG LENLQRVPTV QANMVLIPGS APGETDIILN WQQRKMWRLA ASLDDSGTRS
     TGRYQGGATL FLDNPLSLSD LFYVSAGGAL QRRGDKGTNN LTGHYSLPFG YWTAGMTASR
     YDYYQAVAGL NGDINYRGES ENVAFQLSRL LHRNASQKTT FTYDVLTRSS KNYINDTEVE
     VQRRRTSAWR IGLQHRHFIS QAILDAGISY QRGTRWFGAI PAQEEYFGEA TALSKILRLN
     AQLDIPFVVM AQNLHYNLQY QRQSTNTPLT PQDQFSIGGR WSVRGFNGER TLIADRGWWV
     RNDIGWYLPL PGHELYVGVD YGEVGGRSGA YLLGRHLAGS AVGVRGNVLN TRYDLFAGKP
     LSKPNGFKTD SLAVGFNLNW LY