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CDII_YERMW
ID   CDII_YERMW              Reviewed;         121 AA.
AC   C4SGN8;
DT   08-MAY-2019, integrated into UniProtKB/Swiss-Prot.
DT   08-MAY-2019, sequence version 2.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=Immunity protein CdiI;
DE   AltName: Full=CdiI;
GN   Name=cdiI {ECO:0000303|PubMed:29923643}; ORFNames=ymoll0001_27210;
OS   Yersinia mollaretii (strain ATCC 43969 / DSM 18520 / CIP 103324 / CNY 7263
OS   / WAIP 204).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=349967;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43969 / DSM 18520 / CIP 103324 / CNY 7263 / WAIP 204;
RA   Read T.D., Akmal A., Bishop-Lilly K., Chen P.E., Cook C., Kiley M.P.,
RA   Lentz S., Mateczun A., Nagarajan N., Nolan N., Osborne B.I., Pop M.,
RA   Sozhamannan S., Stewart A.C., Sulakvelidze A., Thomason B., Willner K.,
RA   Zwick M.E.;
RT   "Annotation of the Yersinia mollaretii ATCC 43969 genome.";
RL   Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   FUNCTION.
RC   STRAIN=ATCC 43969 / DSM 18520 / CIP 103324 / CNY 7263 / WAIP 204;
RX   PubMed=29923643; DOI=10.1111/mmi.14007;
RA   Michalska K., Quan Nhan D., Willett J.L.E., Stols L.M., Eschenfeldt W.H.,
RA   Jones A.M., Nguyen J.Y., Koskiniemi S., Low D.A., Goulding C.W.,
RA   Joachimiak A., Hayes C.S.;
RT   "Functional plasticity of antibacterial EndoU toxins.";
RL   Mol. Microbiol. 109:509-527(2018).
CC   -!- FUNCTION: Immunity protein component of a toxin-immunity protein
CC       module, which functions as a cellular contact-dependent growth
CC       inhibition (CDI) system. CDI modules allow bacteria to communicate with
CC       and inhibit the growth of closely related neighboring bacteria in a
CC       contact-dependent fashion. Protects cells against the tRNA endonuclease
CC       activity of cognate toxin CdiA-43969 but not other non-cognate toxins,
CC       inhibits the tRNase activity of the isolated CT fragment of CdiA-43969.
CC       {ECO:0000269|PubMed:29923643}.
CC   -!- SUBUNIT: Forms a 1:1 complex with cognate toxin CdiA.
CC       {ECO:0000305|PubMed:29923643}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EEQ09310.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305|PubMed:29923643};
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DR   EMBL; AALD02000043; EEQ09310.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_049611435.1; NZ_CP054043.1.
DR   AlphaFoldDB; C4SGN8; -.
DR   SMR; C4SGN8; -.
DR   EnsemblBacteria; EEQ09310; EEQ09310; ymoll0001_27210.
DR   GeneID; 57919903; -.
DR   InterPro; IPR041256; CdiI_4.
DR   Pfam; PF18624; CdiI_4; 1.
PE   4: Predicted;
FT   CHAIN           1..121
FT                   /note="Immunity protein CdiI"
FT                   /id="PRO_0000446873"
SQ   SEQUENCE   121 AA;  13927 MW;  1734BFAF1C6AF515 CRC64;
     MKKELFSQQD IDDGLDLIIV SYFDRMYGDG KFLDAIDLLS RKWTLNVDGA YCHFPDMNSY
     DESEHFDGVE FAIGYPPSDA ESVIVSEDIC YQYVRLACEK YLKLHPEDAE KVKDLLTKLP
     A
 
 
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