CDKF1_ORYSJ
ID CDKF1_ORYSJ Reviewed; 479 AA.
AC Q5Z754; A0A0P0WWF8;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Cyclin-dependent kinase F-1;
DE Short=CDKF;1;
DE EC=2.7.11.22;
DE EC=2.7.11.23;
GN Name=CDKF-1; OrderedLocusNames=Os06g0334400, LOC_Os06g22820;
GN ORFNames=OSJNBa0012F14.17;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP INDUCTION, AND GENE FAMILY.
RX PubMed=17443292; DOI=10.1007/s11103-007-9154-y;
RA Guo J., Song J., Wang F., Zhang X.S.;
RT "Genome-wide identification and expression analysis of rice cell cycle
RT genes.";
RL Plant Mol. Biol. 64:349-360(2007).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.22;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.22;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-
CC [DNA-directed RNA polymerase]; Xref=Rhea:RHEA:10216, Rhea:RHEA-
CC COMP:11321, Rhea:RHEA-COMP:11322, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:43176, ChEBI:CHEBI:68546,
CC ChEBI:CHEBI:456216; EC=2.7.11.23;
CC -!- INDUCTION: By auxin. Down-regulated by cytokinin.
CC {ECO:0000269|PubMed:17443292}.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. CMGC Ser/Thr
CC protein kinase family. CDC2/CDKX subfamily. {ECO:0000305}.
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DR EMBL; AP004784; BAD61885.1; -; Genomic_DNA.
DR EMBL; AP008212; BAF19465.1; -; Genomic_DNA.
DR EMBL; AP014962; BAS97580.1; -; Genomic_DNA.
DR EMBL; AK120969; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015644444.1; XM_015788958.1.
DR AlphaFoldDB; Q5Z754; -.
DR SMR; Q5Z754; -.
DR STRING; 4530.OS06T0334400-01; -.
DR iPTMnet; Q5Z754; -.
DR PaxDb; Q5Z754; -.
DR PRIDE; Q5Z754; -.
DR EnsemblPlants; Os06t0334400-01; Os06t0334400-01; Os06g0334400.
DR GeneID; 4340934; -.
DR Gramene; Os06t0334400-01; Os06t0334400-01; Os06g0334400.
DR KEGG; osa:4340934; -.
DR eggNOG; KOG0594; Eukaryota.
DR InParanoid; Q5Z754; -.
DR OMA; RWMIQIL; -.
DR OrthoDB; 683664at2759; -.
DR Proteomes; UP000000763; Chromosome 6.
DR Proteomes; UP000059680; Chromosome 6.
DR ExpressionAtlas; Q5Z754; baseline and differential.
DR Genevisible; Q5Z754; OS.
DR GO; GO:0016592; C:mediator complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019912; F:cyclin-dependent protein kinase activating kinase activity; IBA:GO_Central.
DR GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR GO; GO:0008353; F:RNA polymerase II CTD heptapeptide repeat kinase activity; IBA:GO_Central.
DR GO; GO:0010078; P:maintenance of root meristem identity; IEA:EnsemblPlants.
DR GO; GO:0006468; P:protein phosphorylation; IBA:GO_Central.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR Pfam; PF00069; Pkinase; 2.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Kinase; Nucleotide-binding; Phosphoprotein;
KW Reference proteome; Serine/threonine-protein kinase; Transferase.
FT CHAIN 1..479
FT /note="Cyclin-dependent kinase F-1"
FT /id="PRO_0000296105"
FT DOMAIN 24..419
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT REGION 429..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 146
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159,
FT ECO:0000255|PROSITE-ProRule:PRU10027"
FT BINDING 30..38
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 53
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT MOD_RES 291
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250"
FT CONFLICT 253
FT /note="N -> D (in Ref. 4; AK120969)"
FT /evidence="ECO:0000305"
FT CONFLICT 394
FT /note="S -> G (in Ref. 4; AK120969)"
FT /evidence="ECO:0000305"
FT CONFLICT 450
FT /note="F -> L (in Ref. 4; AK120969)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 479 AA; 52073 MW; 0FA906213F770759 CRC64;
MAIGGGGGGG SWSIHGRPDV TSRYEVLGRA GSGAYADVYR GRRRSDGAPV ALKEVHDAVS
ARREADALLA AAPSRHVVAL LDHFPGGDHD DDVLVLEWLP LDLSAVVRAA AAARPSALPA
AQRKRWMLQV LEGVAACHSA GVVHRDLKPA NLLISEDGVL KVADLGQARI LQETGTYQGM
HPYEQSSGVE PWVSQQRAVL HGVKENHPSH DSETQTGQEP ERLTAADYLH EMDQLRAKST
HGDVDKMSLQ DGNASCLATC STADIDDDPF RASYSYDAEE GMLEEESGAF TSCVGTRWFR
APELLYGSTN YGQEVDLWSL GCILAELFNL EPIFPGTSDI DQIGRIISVL GNITEETFPG
CSNLPDYNKI FFNKVEKPIG LEACLPDRSA SEVSIIKRLL CYDPTKRASA ADLLNDPYFA
EEPLPVPIEG LQVPESKDED DDSTEEWANF RGGDSDSDFD EFGSMDVTKT DKGFSIRFS
