CDT5_ORYSI
ID CDT5_ORYSI Reviewed; 54 AA.
AC B8AYM8;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 35.
DE RecName: Full=Protein CADMIUM TOLERANCE 5 {ECO:0000305};
DE Short=Cd tolerant 5 {ECO:0000305};
DE Short=OsCDT5 {ECO:0000305};
GN Name=CDT5 {ECO:0000305}; ORFNames=OsI_18665 {ECO:0000312|EMBL:EEC78619.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Confers resistance to heavy metal ions (e.g. cadmium
CC (CdCl(2)) and copper (CuCl(2))) by chelating them at the plasma
CC membrane of root cells, thus stopping their entry and reducing their
CC accumulation. {ECO:0000250|UniProtKB:Q5VSB5}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q5VSB5};
CC Single-pass membrane protein {ECO:0000255}. Secreted, cell wall
CC {ECO:0000250|UniProtKB:Q5VSB5}.
CC -!- SIMILARITY: Belongs to the CYSTM1 family. {ECO:0000305}.
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DR EMBL; CM000130; EEC78619.1; -; Genomic_DNA.
DR STRING; 39946.B8AYM8; -.
DR EnsemblPlants; BGIOSGA018704-TA; BGIOSGA018704-PA; BGIOSGA018704.
DR Gramene; BGIOSGA018704-TA; BGIOSGA018704-PA; BGIOSGA018704.
DR HOGENOM; CLU_156676_2_0_1; -.
DR OMA; MSYPQPQ; -.
DR Proteomes; UP000007015; Chromosome 5.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009505; C:plant-type cell wall; ISS:UniProtKB.
DR GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR GO; GO:0046872; F:metal ion binding; ISS:UniProtKB.
DR GO; GO:0140487; F:metal ion sequestering activity; ISS:UniProtKB.
DR GO; GO:1990748; P:cellular detoxification; ISS:UniProtKB.
DR GO; GO:0071585; P:detoxification of cadmium ion; ISS:UniProtKB.
DR GO; GO:0010273; P:detoxification of copper ion; ISS:UniProtKB.
DR InterPro; IPR028144; CYSTM_dom.
DR Pfam; PF12734; CYSTM; 1.
PE 3: Inferred from homology;
KW Cell membrane; Cell wall; Membrane; Metal-binding; Reference proteome;
KW Secreted; Stress response; Transmembrane; Transmembrane helix.
FT CHAIN 1..54
FT /note="Protein CADMIUM TOLERANCE 5"
FT /id="PRO_0000454820"
FT TRANSMEM 24..40
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 54 AA; 6324 MW; C3823DDC5CF639ED CRC64;
MYNPPSAQEM TYKDHVQRRH EEKGCLYACL FTLCCCFCCY ETCECCLETL CCCC
