CE024_MOUSE
ID CE024_MOUSE Reviewed; 188 AA.
AC Q80X32; Q8C2G2;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=UPF0461 protein C5orf24 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Swiss Webster / NIH;
RA Konstantinopoulou V.;
RT "Physical and hematopoietic transcript map of a 5q31 critical subregion
RT associated with the 5q- syndrome.";
RL Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Colon;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-78.
RC STRAIN=NOD; TISSUE=Thymus;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- SIMILARITY: Belongs to the UPF0461 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC40508.2; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AJ492504; CAD37799.1; -; mRNA.
DR EMBL; BC051430; AAH51430.1; -; mRNA.
DR EMBL; AK088693; BAC40508.2; ALT_INIT; mRNA.
DR CCDS; CCDS26552.1; -.
DR RefSeq; NP_851795.1; NM_181278.2.
DR AlphaFoldDB; Q80X32; -.
DR IntAct; Q80X32; 1.
DR STRING; 10090.ENSMUSP00000055271; -.
DR iPTMnet; Q80X32; -.
DR PhosphoSitePlus; Q80X32; -.
DR EPD; Q80X32; -.
DR jPOST; Q80X32; -.
DR MaxQB; Q80X32; -.
DR PaxDb; Q80X32; -.
DR PeptideAtlas; Q80X32; -.
DR PRIDE; Q80X32; -.
DR Antibodypedia; 45237; 76 antibodies from 15 providers.
DR DNASU; 78521; -.
DR Ensembl; ENSMUST00000057844; ENSMUSP00000055271; ENSMUSG00000045767.
DR GeneID; 78521; -.
DR KEGG; mmu:78521; -.
DR UCSC; uc007qrx.1; mouse.
DR MGI; MGI:1925771; B230219D22Rik.
DR VEuPathDB; HostDB:ENSMUSG00000045767; -.
DR eggNOG; ENOG502RZTV; Eukaryota.
DR GeneTree; ENSGT00390000014889; -.
DR HOGENOM; CLU_090677_0_0_1; -.
DR InParanoid; Q80X32; -.
DR OMA; QGMHKAM; -.
DR OrthoDB; 1331530at2759; -.
DR PhylomeDB; Q80X32; -.
DR TreeFam; TF333072; -.
DR BioGRID-ORCS; 78521; 1 hit in 71 CRISPR screens.
DR PRO; PR:Q80X32; -.
DR Proteomes; UP000000589; Chromosome 13.
DR RNAct; Q80X32; protein.
DR Bgee; ENSMUSG00000045767; Expressed in dorsal pancreas and 249 other tissues.
DR Genevisible; Q80X32; MM.
DR InterPro; IPR040419; DUF5568.
DR PANTHER; PTHR31894; PTHR31894; 1.
DR Pfam; PF17724; DUF5568; 1.
PE 2: Evidence at transcript level;
KW Isopeptide bond; Phosphoprotein; Reference proteome; Ubl conjugation.
FT CHAIN 1..188
FT /note="UPF0461 protein C5orf24 homolog"
FT /id="PRO_0000295709"
FT REGION 80..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 37
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7Z6I8"
FT MOD_RES 121
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7Z6I8"
FT MOD_RES 180
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7Z6I8"
FT CROSSLNK 75
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q7Z6I8"
FT CROSSLNK 184
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q7Z6I8"
SQ SEQUENCE 188 AA; 20139 MW; ECAB59940BCBD7AC CRC64;
MMHPVAGSNP AFCGPGKPSC LNEDAMRAAD QFDLYSSQQN KYSHTVSHKP MVCQRQDPLN
ETHLQPTSGR NIEIKDELKK KKNLNRSGKR GRPSGTTKSA GYRTSTGRPL GTTKAAGFKT
SPGRPLGTTK AAGYKVSPGR PPGSIKALSR LADLGYGCGT AAFPYPMMHS RVVHGLQETS
GEVKPPSE