CE034_MOUSE
ID CE034_MOUSE Reviewed; 639 AA.
AC Q3UJC8; Q3TUB6; Q3UF19; Q78HE1; Q8K3D5; Q9CUS5; Q9D822;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Uncharacterized protein C5orf34 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=C57BL/6J;
RC TISSUE=Brain, Head, Kidney, Small intestine, and Sympathetic ganglion;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=Czech II; TISSUE=Mammary gland, and Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q3UJC8-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q3UJC8-2; Sequence=VSP_027120, VSP_027121;
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB25748.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAE36055.1; Type=Frameshift; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK008565; BAB25748.1; ALT_FRAME; mRNA.
DR EMBL; AK014735; BAB29525.3; -; mRNA.
DR EMBL; AK146515; BAE27227.1; -; mRNA.
DR EMBL; AK149119; BAE28742.1; -; mRNA.
DR EMBL; AK160863; BAE36055.1; ALT_FRAME; mRNA.
DR EMBL; BC021327; AAH21327.1; -; mRNA.
DR EMBL; BC030738; AAH30738.1; -; mRNA.
DR CCDS; CCDS49373.1; -. [Q3UJC8-1]
DR RefSeq; NP_001107022.1; NM_001113550.1. [Q3UJC8-1]
DR RefSeq; NP_080403.4; NM_026127.4. [Q3UJC8-1]
DR RefSeq; XP_006517806.1; XM_006517743.1. [Q3UJC8-1]
DR RefSeq; XP_006517807.1; XM_006517744.1. [Q3UJC8-1]
DR RefSeq; XP_006517808.1; XM_006517745.1.
DR RefSeq; XP_006517809.1; XM_006517746.1.
DR RefSeq; XP_006517810.1; XM_006517747.1. [Q3UJC8-1]
DR RefSeq; XP_006517811.1; XM_006517748.1. [Q3UJC8-1]
DR AlphaFoldDB; Q3UJC8; -.
DR STRING; 10090.ENSMUSP00000026519; -.
DR PhosphoSitePlus; Q3UJC8; -.
DR EPD; Q3UJC8; -.
DR PaxDb; Q3UJC8; -.
DR PRIDE; Q3UJC8; -.
DR Antibodypedia; 50296; 23 antibodies from 7 providers.
DR DNASU; 67392; -.
DR Ensembl; ENSMUST00000026519; ENSMUSP00000026519; ENSMUSG00000062822. [Q3UJC8-1]
DR Ensembl; ENSMUST00000224312; ENSMUSP00000153150; ENSMUSG00000062822. [Q3UJC8-1]
DR Ensembl; ENSMUST00000225186; ENSMUSP00000153079; ENSMUSG00000062822. [Q3UJC8-1]
DR Ensembl; ENSMUST00000225726; ENSMUSP00000153338; ENSMUSG00000062822. [Q3UJC8-2]
DR GeneID; 67392; -.
DR KEGG; mmu:67392; -.
DR UCSC; uc007rzf.2; mouse. [Q3UJC8-2]
DR UCSC; uc007rzh.2; mouse. [Q3UJC8-1]
DR MGI; MGI:1914642; 4833420G17Rik.
DR VEuPathDB; HostDB:ENSMUSG00000062822; -.
DR eggNOG; ENOG502QSYT; Eukaryota.
DR GeneTree; ENSGT00500000044987; -.
DR HOGENOM; CLU_029198_0_0_1; -.
DR InParanoid; Q3UJC8; -.
DR OMA; HHSCCAV; -.
DR OrthoDB; 833549at2759; -.
DR PhylomeDB; Q3UJC8; -.
DR TreeFam; TF328443; -.
DR BioGRID-ORCS; 67392; 3 hits in 73 CRISPR screens.
DR PRO; PR:Q3UJC8; -.
DR Proteomes; UP000000589; Chromosome 13.
DR RNAct; Q3UJC8; protein.
DR Bgee; ENSMUSG00000062822; Expressed in metanephric proximal tubule and 253 other tissues.
DR ExpressionAtlas; Q3UJC8; baseline and differential.
DR Genevisible; Q3UJC8; MM.
DR InterPro; IPR027865; DUF4520.
DR InterPro; IPR027830; DUF4524.
DR Pfam; PF15016; DUF4520; 1.
DR Pfam; PF15025; DUF4524; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..639
FT /note="Uncharacterized protein C5orf34 homolog"
FT /id="PRO_0000295898"
FT VAR_SEQ 389..390
FT /note="RE -> VS (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_027120"
FT VAR_SEQ 391..639
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_027121"
FT CONFLICT 10
FT /note="V -> A (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
FT CONFLICT 34
FT /note="S -> F (in Ref. 1; BAB25748)"
FT /evidence="ECO:0000305"
FT CONFLICT 118
FT /note="M -> T (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
FT CONFLICT 190
FT /note="E -> G (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
FT CONFLICT 220
FT /note="S -> T (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
FT CONFLICT 230
FT /note="G -> S (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
FT CONFLICT 236
FT /note="V -> M (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
FT CONFLICT 248
FT /note="A -> S (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
FT CONFLICT 287
FT /note="C -> V (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
FT CONFLICT 293
FT /note="T -> M (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
FT CONFLICT 322
FT /note="Q -> R (in Ref. 1; BAE28742)"
FT /evidence="ECO:0000305"
FT CONFLICT 325
FT /note="P -> S (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
FT CONFLICT 346
FT /note="Y -> F (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
FT CONFLICT 529
FT /note="Y -> C (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
FT CONFLICT 550
FT /note="Q -> R (in Ref. 2; AAH21327)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 639 AA; 72263 MW; 1BC70D8DD2CC2B2E CRC64;
MGMAAEVRMV LYEDDSVQVH YACGSTLQLS PCGSEFLFEK ALPPSTHPLE QPERIRQRTH
FVISNYREQL QRALDFRNSS ATCPFLSESI IPPERKKHIF IDFSEVEWPS LDRDDCIMYS
ESGVVKITSL DGHAYLCLPR SQHEFTVHFL CKVSQRPDSS GILSETQNQD PKNKLVEKTR
KVCRCGNLSE QTLRNKENEP PYQILKSKNA SVNTCCVNDS EGRGELPSLG TNHRCVYAWV
KQAWSVAACP EAWKHPLSLA LRFYNKVRAA SEIDADFPAS SIVTSDCPEE RGTEVSVLPR
ALLLSCPAPH MHRWTFCDSL LQRQPDAEDF SYPELVKVVW YKGVTYRLTH KNVNSIEIFP
GDGSVFKSEG AHFGNYFTYY PSQEESEKRE EKTYSVNNLP PDRPGNFFSV RSLIKQATRI
LQHCAKIRLS LSHNYRVCCW KMAPGVSVST ILPVLLKESL IPGVGRFLAY SDDKVHAVFL
DGVTVTLNWH LSSSAEKKQV DQGLSFGWCR LTFPDGQDQL IPTEHPGAYE RYVTSVISWC
RGLTQTSPRQ VPTHLSPALK ENWSVASELE KIQKFNWLLE NSGVLNLTSS KNEQCSGHCK
SGSSETLLEA TNEERVSVAL KRTSEILQDI DRLLSLSRK
