ID   CE052_HUMAN             Reviewed;         159 AA.
AC   A6NGY3;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Uncharacterized protein C5orf52;
GN   Name=C5orf52;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A.,
RA   Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R.,
RA   Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L.,
RA   Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N.,
RA   Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J.,
RA   Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A.,
RA   Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 41-159.
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; AC008694; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BG721329; -; NOT_ANNOTATED_CDS; mRNA.
DR   CCDS; CCDS47329.1; -.
DR   RefSeq; NP_001138604.1; NM_001145132.1.
DR   RefSeq; XP_011532718.1; XM_011534416.1.
DR   AlphaFoldDB; A6NGY3; -.
DR   SMR; A6NGY3; -.
DR   STRING; 9606.ENSP00000387027; -.
DR   iPTMnet; A6NGY3; -.
DR   PhosphoSitePlus; A6NGY3; -.
DR   BioMuta; C5orf52; -.
DR   MassIVE; A6NGY3; -.
DR   PaxDb; A6NGY3; -.
DR   PeptideAtlas; A6NGY3; -.
DR   PRIDE; A6NGY3; -.
DR   Antibodypedia; 63557; 7 antibodies from 2 providers.
DR   DNASU; 100190949; -.
DR   Ensembl; ENST00000409999.4; ENSP00000387027.3; ENSG00000187658.7.
DR   GeneID; 100190949; -.
DR   KEGG; hsa:100190949; -.
DR   MANE-Select; ENST00000409999.4; ENSP00000387027.3; NM_001145132.2; NP_001138604.1.
DR   UCSC; uc011ddt.3; human.
DR   CTD; 100190949; -.
DR   GeneCards; C5orf52; -.
DR   HGNC; HGNC:35121; C5orf52.
DR   HPA; ENSG00000187658; Tissue enriched (testis).
DR   neXtProt; NX_A6NGY3; -.
DR   OpenTargets; ENSG00000187658; -.
DR   PharmGKB; PA164717340; -.
DR   VEuPathDB; HostDB:ENSG00000187658; -.
DR   eggNOG; ENOG502SDG0; Eukaryota.
DR   GeneTree; ENSGT00390000011578; -.
DR   HOGENOM; CLU_116339_0_0_1; -.
DR   InParanoid; A6NGY3; -.
DR   OMA; ARPQICF; -.
DR   OrthoDB; 1368756at2759; -.
DR   PhylomeDB; A6NGY3; -.
DR   TreeFam; TF338723; -.
DR   PathwayCommons; A6NGY3; -.
DR   SignaLink; A6NGY3; -.
DR   BioGRID-ORCS; 100190949; 10 hits in 1038 CRISPR screens.
DR   GenomeRNAi; 100190949; -.
DR   Pharos; A6NGY3; Tdark.
DR   PRO; PR:A6NGY3; -.
DR   Proteomes; UP000005640; Chromosome 5.
DR   RNAct; A6NGY3; protein.
DR   Bgee; ENSG00000187658; Expressed in left testis and 33 other tissues.
DR   InterPro; IPR038935; C5orf52.
DR   PANTHER; PTHR35666; PTHR35666; 1.
DR   Pfam; PF17666; DUF5528; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..159
FT                   /note="Uncharacterized protein C5orf52"
FT                   /id="PRO_0000341210"
FT   REGION          1..57
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   159 AA;  17908 MW;  2708F277E8EBC76D CRC64;
     MTQPTRPSVT CDQGSSTIGG TAAQATTSSS ATSGSNYQRD RLGRRPEIGV GGQPQICFPR
     PRSAQQPVLF SLMNSSEAAM KKTLPKSHLS RVIIHDNRIT QRIYEMEVSA LEKTKKKISH
     YYEHLKKKFM TEQLRKLGRW REESVNSNRY LTFGIPPPV