CE052_MOUSE
ID CE052_MOUSE Reviewed; 168 AA.
AC Q9CR34; Q3TSB3;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Uncharacterized protein C5orf52 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=C57BL/6J; TISSUE=Egg, and Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9CR34-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9CR34-2; Sequence=VSP_034220;
CC -!- SEQUENCE CAUTION:
CC Sequence=BAE36762.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AK006513; BAB24627.1; -; mRNA.
DR EMBL; AK015005; BAB29667.1; -; mRNA.
DR EMBL; AK049235; BAC33627.1; -; mRNA.
DR EMBL; AK162162; BAE36762.1; ALT_INIT; mRNA.
DR EMBL; AL731853; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC048445; AAH48445.1; -; mRNA.
DR CCDS; CCDS24368.1; -. [Q9CR34-1]
DR RefSeq; NP_080426.1; NM_026150.3. [Q9CR34-1]
DR AlphaFoldDB; Q9CR34; -.
DR STRING; 10090.ENSMUSP00000020712; -.
DR iPTMnet; Q9CR34; -.
DR PhosphoSitePlus; Q9CR34; -.
DR PaxDb; Q9CR34; -.
DR PRIDE; Q9CR34; -.
DR Antibodypedia; 63557; 7 antibodies from 2 providers.
DR DNASU; 67430; -.
DR Ensembl; ENSMUST00000020712; ENSMUSP00000020712; ENSMUSG00000020434. [Q9CR34-1]
DR GeneID; 67430; -.
DR KEGG; mmu:67430; -.
DR UCSC; uc007hts.2; mouse. [Q9CR34-1]
DR MGI; MGI:1914680; 4921536K21Rik.
DR VEuPathDB; HostDB:ENSMUSG00000020434; -.
DR eggNOG; ENOG502SDG0; Eukaryota.
DR GeneTree; ENSGT00390000011578; -.
DR HOGENOM; CLU_116339_0_0_1; -.
DR InParanoid; Q9CR34; -.
DR OMA; ARPQICF; -.
DR OrthoDB; 1368756at2759; -.
DR PhylomeDB; Q9CR34; -.
DR TreeFam; TF338723; -.
DR BioGRID-ORCS; 67430; 6 hits in 71 CRISPR screens.
DR PRO; PR:Q9CR34; -.
DR Proteomes; UP000000589; Chromosome 11.
DR RNAct; Q9CR34; protein.
DR Bgee; ENSMUSG00000020434; Expressed in animal zygote and 36 other tissues.
DR Genevisible; Q9CR34; MM.
DR InterPro; IPR038935; C5orf52.
DR PANTHER; PTHR35666; PTHR35666; 1.
DR Pfam; PF17666; DUF5528; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..168
FT /note="Uncharacterized protein C5orf52 homolog"
FT /id="PRO_0000341211"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..84
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_034220"
SQ SEQUENCE 168 AA; 19722 MW; 294FAD1595B63893 CRC64;
MVLGLASFPE SLSSQSETAT QPRRPSVKWD LGSDYRKGTE ETTASGSNFR RERLDSQPDL
GLHVQPQIYF LRPRSPLPKL LFSLMNTNDA NVKKLLPKSH LSRVIIRDNL NAQRICEMEM
KASDKTKRKM SYLYDHLKKK FMMDQLRKMI RWRRDSQSTQ DYLDKERV
