ID   CE3E_HYPCU              Reviewed;          63 AA.
AC   P50721;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Hyphancin-3E;
DE   AltName: Full=Cecropin-A1;
DE   AltName: Full=Hyphancin-IIIE;
DE   Flags: Precursor;
OS   Hyphantria cunea (Fall webworm moth) (Phalaena cunea).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Erebidae; Arctiinae; Hyphantria.
OX   NCBI_TaxID=39466;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Park S.-S., Shin S.W., Kim M.K., Park D.S., Oh H.W., Park H.Y.;
RL   Submitted (MAR-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Has antibacterial activity.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the cecropin family. {ECO:0000305}.
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DR   EMBL; U23832; AAB39001.1; -; mRNA.
DR   AlphaFoldDB; P50721; -.
DR   SMR; P50721; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019731; P:antibacterial humoral response; IEA:InterPro.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:UniProt.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   InterPro; IPR000875; Cecropin.
DR   Pfam; PF00272; Cecropin; 1.
DR   PROSITE; PS00268; CECROPIN; 1.
PE   3: Inferred from homology;
KW   Amidation; Antibiotic; Antimicrobial; Immunity; Innate immunity; Secreted;
KW   Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   PROPEP          23..26
FT                   /note="Removed by a dipeptidylpeptidase"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000004867"
FT   CHAIN           27..61
FT                   /note="Hyphancin-3E"
FT                   /id="PRO_0000004868"
FT   MOD_RES         61
FT                   /note="Leucine amide"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   63 AA;  6898 MW;  C09E5F1FE4483021 CRC64;
     MNFSRILFFV FTCFVALASV SGAPEPRWKF FKKIERVGQN VRDGLIKAGP AIQVLGAAKA
     LGK