ID   CEC4_BOMMO              Reviewed;          35 AA.
AC   P14666;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Cecropin;
DE   AltName: Full=Antibacterial peptide CM-IV;
OS   Bombyx mori (Silk moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Bombycidae; Bombycinae; Bombyx.
OX   NCBI_TaxID=7091;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT ILE-35.
RX   PubMed=3318666; DOI=10.1146/annurev.mi.41.100187.000535;
RA   Boman H.G., Hultmark D.;
RT   "Cell-free immunity in insects.";
RL   Annu. Rev. Microbiol. 41:103-126(1987).
CC   -!- FUNCTION: Cecropins have lytic and antibacterial activity against
CC       several Gram-positive and Gram-negative bacteria.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the cecropin family. {ECO:0000305}.
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DR   AlphaFoldDB; P14666; -.
DR   SMR; P14666; -.
DR   Proteomes; UP000005204; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019731; P:antibacterial humoral response; IEA:InterPro.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:UniProt.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   InterPro; IPR000875; Cecropin.
DR   Pfam; PF00272; Cecropin; 1.
DR   PROSITE; PS00268; CECROPIN; 1.
PE   1: Evidence at protein level;
KW   Amidation; Antibiotic; Antimicrobial; Direct protein sequencing; Immunity;
KW   Innate immunity; Reference proteome; Secreted.
FT   PEPTIDE         1..35
FT                   /note="Cecropin"
FT                   /id="PRO_0000044679"
FT   MOD_RES         35
FT                   /note="Isoleucine amide"
FT                   /evidence="ECO:0000269|PubMed:3318666"
SQ   SEQUENCE   35 AA;  3763 MW;  5240DEC509117486 CRC64;
     RWKIFKKIEK VGQNIRDGIV KAGPAVAVVG QAATI