ID   CECA_TRINI              Reviewed;          62 AA.
AC   P50724;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Cecropin-A;
DE   Flags: Precursor;
OS   Trichoplusia ni (Cabbage looper).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Noctuidae; Plusiinae; Trichoplusia.
OX   NCBI_TaxID=7111;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8882660; DOI=10.1016/0965-1748(95)00080-1;
RA   Kang D., Liu G., Gunne H., Steiner H.;
RT   "PCR differential display of immune gene expression in Trichoplusia ni.";
RL   Insect Biochem. Mol. Biol. 26:177-184(1996).
CC   -!- FUNCTION: Has antibacterial activity.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the cecropin family. {ECO:0000305}.
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DR   EMBL; U38645; AAA81323.1; -; mRNA.
DR   PIR; T12014; T12014.
DR   AlphaFoldDB; P50724; -.
DR   SMR; P50724; -.
DR   Proteomes; UP000322000; Genome assembly.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019731; P:antibacterial humoral response; IEA:InterPro.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:UniProt.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   InterPro; IPR000875; Cecropin.
DR   Pfam; PF00272; Cecropin; 1.
DR   PROSITE; PS00268; CECROPIN; 1.
PE   3: Inferred from homology;
KW   Amidation; Antibiotic; Antimicrobial; Immunity; Innate immunity;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   PROPEP          21..24
FT                   /note="Removed by a dipeptidylpeptidase"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000004881"
FT   CHAIN           25..60
FT                   /note="Cecropin-A"
FT                   /id="PRO_0000004882"
FT   MOD_RES         60
FT                   /note="Threonine amide"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   62 AA;  6720 MW;  849214CB8D2D44F3 CRC64;
     MNLVKILFCV FACLVFTVTA VPEPRWKFFK KIEKVGQNIR DGIIKAGPAV AVVGQAASIT
     GK