ID   CECB_ANTPE              Reviewed;          35 AA.
AC   P01509;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 2.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Cecropin-B;
OS   Antheraea pernyi (Chinese oak silk moth) (Bombyx pernyi).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Saturniidae; Saturniinae; Saturniini; Antheraea.
OX   NCBI_TaxID=7119;
RN   [1]
RP   PARTIAL PROTEIN SEQUENCE.
RX   PubMed=6754375; DOI=10.1111/j.1432-1033.1982.tb06858.x;
RA   Qu X.-M., Steiner H., Engstroem A., Bennich H., Boman H.G.;
RT   "Insect immunity: isolation and structure of cecropins B and D from pupae
RT   of the Chinese oak silk moth, Antheraea pernyi.";
RL   Eur. J. Biochem. 127:219-224(1982).
RN   [2]
RP   PROTEIN SEQUENCE, AND AMIDATION AT LEU-35.
RX   PubMed=2962676; DOI=10.1002/bms.1200141118;
RA   Craig A.G., Engstrom A., Bennich H., Kamensky I.;
RT   "Plasma desorption mass spectrometry coupled with conventional peptide
RT   sequencing techniques.";
RL   Biomed. Environ. Mass Spectrom. 14:669-673(1987).
CC   -!- FUNCTION: Cecropins have lytic and antibacterial activity against
CC       several Gram-positive and Gram-negative bacteria.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the cecropin family. {ECO:0000305}.
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DR   PIR; A54725; CKAOBP.
DR   AlphaFoldDB; P01509; -.
DR   SMR; P01509; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019731; P:antibacterial humoral response; IEA:InterPro.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:UniProt.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   InterPro; IPR000875; Cecropin.
DR   Pfam; PF00272; Cecropin; 1.
DR   PROSITE; PS00268; CECROPIN; 1.
PE   1: Evidence at protein level;
KW   Amidation; Antibiotic; Antimicrobial; Direct protein sequencing; Immunity;
KW   Innate immunity; Secreted.
FT   PEPTIDE         1..35
FT                   /note="Cecropin-B"
FT                   /id="PRO_0000044677"
FT   MOD_RES         35
FT                   /note="Leucine amide"
FT                   /evidence="ECO:0000269|PubMed:2962676"
SQ   SEQUENCE   35 AA;  3818 MW;  7AFCBB0A10E16313 CRC64;
     KWKIFKKIEK VGRNIRNGII KAGPAVAVLG EAKAL