ID   CECD_ANTPE              Reviewed;          36 AA.
AC   P01511;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Cecropin-D;
OS   Antheraea pernyi (Chinese oak silk moth) (Bombyx pernyi).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Saturniidae; Saturniinae; Saturniini; Antheraea.
OX   NCBI_TaxID=7119;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT LYS-36.
RX   PubMed=6754375; DOI=10.1111/j.1432-1033.1982.tb06858.x;
RA   Qu X.-M., Steiner H., Engstroem A., Bennich H., Boman H.G.;
RT   "Insect immunity: isolation and structure of cecropins B and D from pupae
RT   of the Chinese oak silk moth, Antheraea pernyi.";
RL   Eur. J. Biochem. 127:219-224(1982).
CC   -!- FUNCTION: Cecropins have lytic and antibacterial activity against
CC       several Gram-positive and Gram-negative bacteria.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the cecropin family. {ECO:0000305}.
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DR   PIR; A01773; CKAODP.
DR   AlphaFoldDB; P01511; -.
DR   SMR; P01511; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019731; P:antibacterial humoral response; IEA:InterPro.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:UniProt.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   InterPro; IPR000875; Cecropin.
DR   Pfam; PF00272; Cecropin; 1.
DR   PROSITE; PS00268; CECROPIN; 1.
PE   1: Evidence at protein level;
KW   Amidation; Antibiotic; Antimicrobial; Direct protein sequencing; Immunity;
KW   Innate immunity; Secreted.
FT   PEPTIDE         1..36
FT                   /note="Cecropin-D"
FT                   /id="PRO_0000044678"
FT   MOD_RES         36
FT                   /note="Lysine amide"
FT                   /evidence="ECO:0000269|PubMed:6754375"
SQ   SEQUENCE   36 AA;  3807 MW;  FDB270F2AC4873B9 CRC64;
     WNPFKELERA GQRVRDAIIS AGPAVATVAQ ATALAK