ID   CECE_BOMMO              Reviewed;          59 AA.
AC   P48821;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Antibacterial peptide enbocin;
DE   AltName: Full=Moricin;
DE   Flags: Precursor;
OS   Bombyx mori (Silk moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Bombycidae; Bombycinae; Bombyx.
OX   NCBI_TaxID=7091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Kim S.H., Je Y.H., Kim K.Y., Kang S.K.;
RT   "Molecular characterization of a new antibacterial peptide gene, enbocin,
RT   from Bombyx mori.";
RL   Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Backokjam;
RA   Kim S.H., Je Y.H., Youn E.Y., Lee D.W., Kim K.Y., Kang S.K.;
RT   "Cloning and expression of enbocin gene encoding a new antibacterial
RT   peptide from Bombyx mori.";
RL   Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Has antibacterial activity against Gram-positive and Gram-
CC       negative bacteria.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the cecropin family. {ECO:0000305}.
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DR   EMBL; U30289; AAC02238.1; -; mRNA.
DR   EMBL; AF049237; AAC05493.1; -; Genomic_DNA.
DR   PIR; JE0161; JE0161.
DR   RefSeq; NP_001037472.1; NM_001044007.1.
DR   AlphaFoldDB; P48821; -.
DR   SMR; P48821; -.
DR   TCDB; 1.C.17.1.3; the cecropin (cecropin) family.
DR   GeneID; 693035; -.
DR   CTD; 693035; -.
DR   HOGENOM; CLU_187909_0_0_1; -.
DR   Proteomes; UP000005204; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019731; P:antibacterial humoral response; IEA:InterPro.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:UniProt.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   InterPro; IPR000875; Cecropin.
DR   Pfam; PF00272; Cecropin; 1.
DR   PROSITE; PS00268; CECROPIN; 1.
PE   3: Inferred from homology;
KW   Amidation; Antibiotic; Antimicrobial; Immunity; Innate immunity;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   PROPEP          21
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000004830"
FT   CHAIN           22..58
FT                   /note="Antibacterial peptide enbocin"
FT                   /id="PRO_0000004831"
FT   MOD_RES         58
FT                   /note="Serine amide"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   59 AA;  6330 MW;  284DF86F22E6DEB5 CRC64;
     MNFTRIIFFL FVVVFATASG KPWNIFKEIE RAVARTRDAV ISAGPAVRTV AAATSVASG