CEC_OIKKI
ID CEC_OIKKI Reviewed; 32 AA.
AC P83420;
DT 15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 42.
DE RecName: Full=Cecropin;
DE Flags: Fragment;
OS Oiketicus kirbyi (Bagworm moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Tineoidea;
OC Psychidae; Oiketicinae; Oiketicus.
OX NCBI_TaxID=201386 {ECO:0000305};
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, TISSUE
RP SPECIFICITY, AND MASS SPECTROMETRY.
RC TISSUE=Hemolymph;
RA Bulet P.;
RL Submitted (JUL-2002) to UniProtKB.
CC -!- FUNCTION: Cecropins have lytic and antibacterial activity against
CC several Gram-positive and Gram-negative bacteria. Has also activity
CC against fungi. {ECO:0000269|Ref.1}.
CC -!- SUBUNIT: Monomer. {ECO:0000269|Ref.1, ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1, ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Hemolymph. {ECO:0000269|Ref.1, ECO:0000305}.
CC -!- MASS SPECTROMETRY: Mass=3818.89; Method=MALDI;
CC Evidence={ECO:0000269|Ref.1};
CC -!- SIMILARITY: Belongs to the cecropin family. {ECO:0000305}.
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DR AlphaFoldDB; P83420; -.
DR SMR; P83420; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0019731; P:antibacterial humoral response; IEA:InterPro.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:UniProt.
DR GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR InterPro; IPR000875; Cecropin.
DR Pfam; PF00272; Cecropin; 1.
DR PROSITE; PS00268; CECROPIN; 1.
PE 1: Evidence at protein level;
KW Antibiotic; Antimicrobial; Direct protein sequencing; Fungicide; Immunity;
KW Innate immunity; Secreted.
FT CHAIN 1..>32
FT /note="Cecropin"
FT /id="PRO_0000127106"
FT NON_TER 32
FT /evidence="ECO:0000305"
SQ SEQUENCE 32 AA; 3434 MW; F6942D09A7BDC1F0 CRC64;
WKPFKKIEKA VRRVRDGVAK AGPAVAVVGQ AT