ACCH5_ARATH
ID ACCH5_ARATH Reviewed; 398 AA.
AC Q43383; Q9LR82;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 2.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=1-aminocyclopropane-1-carboxylate oxidase homolog 5;
DE EC=1.14.-.-;
GN Name=2A6; OrderedLocusNames=At1g03410; ORFNames=F21B7.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 35-398, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia; TISSUE=Etiolated seedling;
RX PubMed=7579161; DOI=10.1007/bf00019127;
RA Trentmann S.M., Kende H.;
RT "Analysis of Arabidopsis cDNA that shows homology to the tomato E8 cDNA.";
RL Plant Mol. Biol. 29:161-166(1995).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000255|PROSITE-ProRule:PRU00805};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000255|PROSITE-
CC ProRule:PRU00805};
CC -!- TISSUE SPECIFICITY: Expressed in etiolated seedlings, leaves, stems and
CC flowers. {ECO:0000269|PubMed:7579161}.
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF86540.1; Type=Erroneous gene model prediction; Note=The predicted gene At1g03410 has been split into 2 genes: At1g03400 and At1g03410.; Evidence={ECO:0000305};
CC Sequence=BAE98763.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAA58151.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC002560; AAF86540.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE27569.1; -; Genomic_DNA.
DR EMBL; AK226654; BAE98763.1; ALT_INIT; mRNA.
DR EMBL; X83096; CAA58151.1; ALT_INIT; mRNA.
DR PIR; S59548; S59548.
DR RefSeq; NP_001323192.1; NM_001331410.1.
DR RefSeq; NP_171840.2; NM_100223.3.
DR AlphaFoldDB; Q43383; -.
DR SMR; Q43383; -.
DR PaxDb; Q43383; -.
DR PRIDE; Q43383; -.
DR ProteomicsDB; 244356; -.
DR EnsemblPlants; AT1G03410.1; AT1G03410.1; AT1G03410.
DR GeneID; 838763; -.
DR Gramene; AT1G03410.1; AT1G03410.1; AT1G03410.
DR KEGG; ath:AT1G03410; -.
DR Araport; AT1G03410; -.
DR TAIR; locus:2020798; AT1G03410.
DR eggNOG; KOG0143; Eukaryota.
DR HOGENOM; CLU_010119_0_0_1; -.
DR InParanoid; Q43383; -.
DR OrthoDB; 755305at2759; -.
DR PRO; PR:Q43383; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q43383; baseline and differential.
DR Genevisible; Q43383; AT.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.330; -; 1.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 2: Evidence at transcript level;
KW Iron; Metal-binding; Oxidoreductase; Reference proteome.
FT CHAIN 1..398
FT /note="1-aminocyclopropane-1-carboxylate oxidase homolog 5"
FT /id="PRO_0000408280"
FT DOMAIN 247..347
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 271
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 273
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 327
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 338
FT /ligand="2-oxoglutarate"
FT /ligand_id="ChEBI:CHEBI:16810"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
SQ SEQUENCE 398 AA; 44846 MW; BFF7C5A6BC08D8CB CRC64;
MGHDSFCYLI VLRCALRCGI IALMQICALQ KKERRSKMES SDRSSQAKAF DETKTGVKGL
VASGIKEIPA MFHTPPDTLT SLKQTAPPSQ QLTIPTVDLK GGSMDLISRR SVVEKIGDAA
ERWGFFQVVN HGISVEVMER MKEGIRRFHE QDPEVKKRFY SRDHTRDVLY YSNIDLHTCN
KAANWRDTLA CYMAPDPPKL QDLPAVCGEI MMEYSKQLMT LGEFLFELLS EALGLNPNHL
KDMGCAKSHI MFGQYYPPCP QPDLTLGISK HTDFSFITIL LQDNIGGLQV IHDQCWVDVS
PVPGALVINI GDLLQLISND KFISAEHRVI ANGSSEPRIS MPCFVSTFMK PNPRIYGPIK
ELLSEQNPAK YRDLTITEFS NTFRSQTISH PALHHFRI
