CEDA_SULAC
ID CEDA_SULAC Reviewed; 260 AA.
AC Q4JB69;
DT 05-OCT-2016, integrated into UniProtKB/Swiss-Prot.
DT 02-AUG-2005, sequence version 1.
DT 25-MAY-2022, entry version 55.
DE RecName: Full=DNA import protein CedA {ECO:0000305};
DE AltName: Full=Crenarchaeal system for exchange of DNA protein A {ECO:0000303|PubMed:26884154};
GN Name=cedA {ECO:0000303|PubMed:26884154};
GN OrderedLocusNames=Saci_0568 {ECO:0000312|EMBL:AAY79960.1};
OS Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC
OS 15157 / NCIMB 11770).
OC Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=330779;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770;
RX PubMed=15995215; DOI=10.1128/jb.187.14.4992-4999.2005;
RA Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E.,
RA Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.;
RT "The genome of Sulfolobus acidocaldarius, a model organism of the
RT Crenarchaeota.";
RL J. Bacteriol. 187:4992-4999(2005).
RN [2]
RP FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, INDUCTION, AND DISRUPTION
RP PHENOTYPE.
RC STRAIN=JDS22, and MW001;
RX PubMed=26884154; DOI=10.1073/pnas.1513740113;
RA van Wolferen M., Wagner A., van der Does C., Albers S.V.;
RT "The archaeal Ced system imports DNA.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:2496-2501(2016).
CC -!- FUNCTION: Part of the Ced system, which is involved in DNA import.
CC {ECO:0000269|PubMed:26884154}.
CC -!- SUBUNIT: Forms a complex composed of CedA, CedA1 and CedA2.
CC {ECO:0000269|PubMed:26884154}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:26884154};
CC Multi-pass membrane protein {ECO:0000255}.
CC -!- INDUCTION: Up-regulated upon UV stress. {ECO:0000269|PubMed:26884154}.
CC -!- DISRUPTION PHENOTYPE: DNA transfer is completely abolished in deletion
CC mutants. Deletion does not reduce cellular aggregation induced by UV
CC stress. {ECO:0000269|PubMed:26884154}.
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DR EMBL; CP000077; AAY79960.1; -; Genomic_DNA.
DR RefSeq; WP_011277462.1; NC_007181.1.
DR AlphaFoldDB; Q4JB69; -.
DR STRING; 330779.Saci_0568; -.
DR TCDB; 9.A.53.1.1; the crenarchaeal system for exchange of dna (ced) family.
DR EnsemblBacteria; AAY79960; AAY79960; Saci_0568.
DR GeneID; 3473206; -.
DR KEGG; sai:Saci_0568; -.
DR PATRIC; fig|330779.12.peg.547; -.
DR eggNOG; arCOG05930; Archaea.
DR HOGENOM; CLU_1040590_0_0_2; -.
DR OMA; PFRIGRS; -.
DR Proteomes; UP000001018; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..260
FT /note="DNA import protein CedA"
FT /id="PRO_0000437445"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 220..240
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 260 AA; 28418 MW; FBA34AEE9695E384 CRC64;
MLNPFQLLFY SQLLASLTYF IGAAIYALPV PVYGVKKWAP RLITDSIYVV VWNSIYLGVL
LFLGELLSLL GVTWDGYFSW LNNILYIEQS LYLMVKTILT ASNAVPEVSA LIQVVPFGAL
LTVITSALTF TSTLIAVSKI VYQYVAVFIA TGVLFLSIPF RIGRSVGGAF IGSGIVFYVG
LPYLPQFLAA FQMLPTQELN TPPQNASAII DYYVHVVPSI ITSLVIGPVI YIFILVGFSM
GVASLVSGYG SRLPLIIDVF
