ACCH9_ARATH
ID ACCH9_ARATH Reviewed; 365 AA.
AC Q9LSW7; Q0WVA2;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=1-aminocyclopropane-1-carboxylate oxidase homolog 9;
DE EC=1.14.-.-;
GN OrderedLocusNames=At5g43440; ORFNames=MWF20.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000255|PROSITE-ProRule:PRU00805};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000255|PROSITE-
CC ProRule:PRU00805};
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9LSW7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9LSW7-2; Sequence=VSP_041040, VSP_041041;
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000305}.
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DR EMBL; AB025638; BAA97423.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94963.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94964.1; -; Genomic_DNA.
DR EMBL; AY056810; AAL10501.1; -; mRNA.
DR EMBL; AY143873; AAN28812.1; -; mRNA.
DR EMBL; AK226856; BAE98946.1; -; mRNA.
DR RefSeq; NP_001078700.1; NM_001085231.2. [Q9LSW7-2]
DR RefSeq; NP_199157.1; NM_123710.2. [Q9LSW7-1]
DR AlphaFoldDB; Q9LSW7; -.
DR SMR; Q9LSW7; -.
DR STRING; 3702.AT5G43440.1; -.
DR PaxDb; Q9LSW7; -.
DR PRIDE; Q9LSW7; -.
DR ProteomicsDB; 244515; -. [Q9LSW7-1]
DR EnsemblPlants; AT5G43440.1; AT5G43440.1; AT5G43440. [Q9LSW7-1]
DR EnsemblPlants; AT5G43440.2; AT5G43440.2; AT5G43440. [Q9LSW7-2]
DR GeneID; 834364; -.
DR Gramene; AT5G43440.1; AT5G43440.1; AT5G43440. [Q9LSW7-1]
DR Gramene; AT5G43440.2; AT5G43440.2; AT5G43440. [Q9LSW7-2]
DR KEGG; ath:AT5G43440; -.
DR Araport; AT5G43440; -.
DR TAIR; locus:2176456; AT5G43440.
DR eggNOG; KOG0143; Eukaryota.
DR HOGENOM; CLU_010119_0_0_1; -.
DR InParanoid; Q9LSW7; -.
DR OMA; ACYIAPA; -.
DR OrthoDB; 755305at2759; -.
DR PhylomeDB; Q9LSW7; -.
DR BioCyc; ARA:AT5G43440-MON; -.
DR PRO; PR:Q9LSW7; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LSW7; baseline and differential.
DR Genevisible; Q9LSW7; AT.
DR GO; GO:0009815; F:1-aminocyclopropane-1-carboxylate oxidase activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.330; -; 1.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Iron; Metal-binding; Oxidoreductase;
KW Reference proteome.
FT CHAIN 1..365
FT /note="1-aminocyclopropane-1-carboxylate oxidase homolog 9"
FT /id="PRO_0000408284"
FT DOMAIN 214..313
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 238
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 240
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 294
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 304
FT /ligand="2-oxoglutarate"
FT /ligand_id="ChEBI:CHEBI:16810"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT VAR_SEQ 283..290
FT /note="LITNDKFL -> ASSIDASF (in isoform 2)"
FT /evidence="ECO:0000303|Ref.4"
FT /id="VSP_041040"
FT VAR_SEQ 291..365
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.4"
FT /id="VSP_041041"
SQ SEQUENCE 365 AA; 40860 MW; 0A8EDA3D4CC69389 CRC64;
MTEKSAELVR LNELKAFVST KAGVKGLVDT KITEVPRIFH IPSSSTLSNN KPSDIFGLNL
TVPIIDLGDG NTSAARNVLV SKIKEAAENW GFFQVINHGI PLTVLKDIKQ GVRRFHEEDP
EVKKQYFATD FNTRFAYNTN FDIHYSSPMN WKDSFTCYTC PQDPLKPEEI PLACRDVVIE
YSKHVMELGG LLFQLLSEAL GLDSEILKNM DCLKGLLMLC HYYPPCPQPD LTLGISKHTD
NSFITILLQD QIGGLQVLHQ DSWVDVTPVP GALVISIGDF MQLITNDKFL SMEHRVRANR
DGPRISVACF VSSGVFPNST VYGPIKELLS DENPAKYRDI TIPEYTVGYL ASIFDGKSHL
SKFRI
