ID   CEF1_USTMA              Reviewed;         820 AA.
AC   Q4P652; A0A0D1DXS3;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Pre-mRNA-splicing factor CEF1;
GN   Name=CEF1; ORFNames=UMAG_04411;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in pre-mRNA splicing and cell cycle control.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus
CC       {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC   -!- SIMILARITY: Belongs to the CEF1 family. {ECO:0000305}.
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DR   EMBL; CM003153; KIS67310.1; -; Genomic_DNA.
DR   RefSeq; XP_011391106.1; XM_011392804.1.
DR   AlphaFoldDB; Q4P652; -.
DR   SMR; Q4P652; -.
DR   STRING; 5270.UM04411P0; -.
DR   EnsemblFungi; KIS67310; KIS67310; UMAG_04411.
DR   GeneID; 23564605; -.
DR   KEGG; uma:UMAG_04411; -.
DR   VEuPathDB; FungiDB:UMAG_04411; -.
DR   eggNOG; KOG0050; Eukaryota.
DR   HOGENOM; CLU_009082_0_0_1; -.
DR   InParanoid; Q4P652; -.
DR   OMA; PFRTQRE; -.
DR   OrthoDB; 975557at2759; -.
DR   Proteomes; UP000000561; Chromosome 14.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000974; C:Prp19 complex; IBA:GO_Central.
DR   GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   CDD; cd00167; SANT; 1.
DR   InterPro; IPR021786; Cdc5p/Cef1_C.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017930; Myb_dom.
DR   InterPro; IPR001005; SANT/Myb.
DR   Pfam; PF11831; Myb_Cef; 1.
DR   SMART; SM00717; SANT; 2.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS51294; HTH_MYB; 2.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; DNA-binding; mRNA processing; mRNA splicing;
KW   Nucleus; Reference proteome; Repeat; Spliceosome.
FT   CHAIN           1..820
FT                   /note="Pre-mRNA-splicing factor CEF1"
FT                   /id="PRO_0000197105"
FT   DOMAIN          3..58
FT                   /note="HTH myb-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   DOMAIN          59..108
FT                   /note="HTH myb-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   DNA_BIND        31..54
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   DNA_BIND        82..104
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   REGION          114..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          248..294
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          405..476
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          514..560
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          160..205
FT                   /evidence="ECO:0000255"
FT   COILED          526..562
FT                   /evidence="ECO:0000255"
FT   COILED          761..805
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        131..162
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        248..266
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        267..284
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        405..456
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        524..558
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   820 AA;  91766 MW;  5270813B6F8E88F4 CRC64;
     MVRVIIKGGV WKNTEDEILK AAISKYGKNQ WARISSLLVR KTPKQCKARW YEWLDPSIKK
     TEWSKEEDEK LLHLAKLMPT QWRTIAPLVG RTANHCLERY QKLLDQAEAQ DNQATSSSLG
     LIGTGEAVPS ADDVRRLRPG EIDPDPETKP ARPDPIDMDE DEKEMLSEAR ARLANTQGKK
     AKRKARERAL EQSRRLAMLQ KRRELKAAGI TIKQKPKKGS VDYNADVPFE KKPLPGFYDT
     SAETSKSYKA PIGKTLQELN NRNAGPEDAT KSKRQREAEE KNKQAKQPIA GPSDEHIRKL
     KEADQITKRR KLNLPAAQVG QDELEAIVKI GLAGERARFL VQDGSSDATD SLLENYSALD
     SAKATRTPQL AAHEDSVMRE ANHLRLISSM QTPLLGDVNV DLQSSKSSGI QTPGSFVPQT
     PNPLLTPGLR NGQTPASASD SRLHADTSTP QRTPLRDNLG LNVDDSFQAG HETPRELKRA
     RSLAQSHLRQ SLSSLPAPKN DFDIVVDEQD VELQANSSSR LDNEPAMSEE DAAERDARLA
     RQAAEEEARS EARRSQVVRR NLPRPAQVDL SRLHNQIDSR YRDRVELLVA RETAQLLHHD
     ANVHPIAGGK HPEPEAVQFD TLSDTSLITA RELMRKELAE QLGFPGANQE ALKRMVAASL
     NDDEEGMQRL EDALKQQWYE ARNNKSQLVE QLEVTRAKMA RIASQAAKGE KMLTKVLGGY
     QARSVALLNS TKEQFKALQE AAISRETFEY LGRGEQCGKA DRLDSLRKEV ESLARRESMA
     QTAYKLLAEE RSTLQEHCEM LEMELLMRQA ESLNEANLSA