ACCO1_BRAJU
ID ACCO1_BRAJU Reviewed; 320 AA.
AC Q09052;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=1-aminocyclopropane-1-carboxylate oxidase;
DE Short=ACC oxidase;
DE EC=1.14.17.4;
DE AltName: Full=Ethylene-forming enzyme;
DE Short=EFE;
GN Name=ACO;
OS Brassica juncea (Indian mustard) (Sinapis juncea).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3707;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1623202; DOI=10.1007/bf00023409;
RA Pua E.-C., Sim G.-E., Chye M.-L.;
RT "Isolation and sequence analysis of a cDNA clone encoding ethylene-forming
RT enzyme in Brassica juncea (L.) Czern & Coss.";
RL Plant Mol. Biol. 19:541-544(1992).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=1-aminocyclopropane-1-carboxylate + L-ascorbate + O2 = CO2 +
CC ethene + 2 H2O + hydrogen cyanide + L-dehydroascorbate;
CC Xref=Rhea:RHEA:23640, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379,
CC ChEBI:CHEBI:16526, ChEBI:CHEBI:18153, ChEBI:CHEBI:18407,
CC ChEBI:CHEBI:38290, ChEBI:CHEBI:58360, ChEBI:CHEBI:58539;
CC EC=1.14.17.4;
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC -!- PATHWAY: Alkene biosynthesis; ethylene biosynthesis via S-adenosyl-L-
CC methionine; ethylene from S-adenosyl-L-methionine: step 2/2.
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000305}.
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DR EMBL; Z11750; CAA77807.1; -; mRNA.
DR PIR; S22488; S22488.
DR AlphaFoldDB; Q09052; -.
DR SMR; Q09052; -.
DR UniPathway; UPA00384; UER00563.
DR GO; GO:0009815; F:1-aminocyclopropane-1-carboxylate oxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009693; P:ethylene biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0009835; P:fruit ripening; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.330; -; 1.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 2: Evidence at transcript level;
KW Ethylene biosynthesis; Fruit ripening; Iron; Metal-binding; Oxidoreductase;
KW Vitamin C.
FT CHAIN 1..320
FT /note="1-aminocyclopropane-1-carboxylate oxidase"
FT /id="PRO_0000067253"
FT DOMAIN 156..256
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 180
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 182
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 237
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
SQ SEQUENCE 320 AA; 36406 MW; 3E597FB902682AAC CRC64;
MEKNIKFPVV DLSKLIGEER DQTMALINDA CENWGFFEIV NHGLPHDLMD NAEKMTKEHY
KISMEQKFND MLKSKGLENL EREVEDVDWE STFYLRHLPQ SNLYDIPDMS DEYRTAMKDF
GKRLENLAED LLDLLCENLG LEKGYLKKVF HGTKGPTFGT KVSNYPACPK PEMIKGLRAH
TDAGGIILLF QDDKVTGLQL LKDGDWIDVP PLNHSIVINL GDQLEVITNG RYKSMMHRVV
TQKEGNRMSI ASFYNPGSDA EISPASSLAC KETEYPSFVF DDYMKLYAGV KFQPKEPRFE
AMKNANAVTE LNPTAAVETF
