CEH62_CAEEL
ID CEH62_CAEEL Reviewed; 416 AA.
AC Q09602;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Homeobox protein ceh-62 {ECO:0000312|WormBase:R06F6.6};
GN Name=ceh-62 {ECO:0000312|WormBase:R06F6.6};
GN ORFNames=R06F6.6 {ECO:0000312|WormBase:R06F6.6};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA86776.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; Z46794; CAA86776.1; ALT_SEQ; Genomic_DNA.
DR PIR; T23977; T23977.
DR RefSeq; NP_496326.2; NM_063925.4.
DR AlphaFoldDB; Q09602; -.
DR SMR; Q09602; -.
DR BioGRID; 52329; 1.
DR IntAct; Q09602; 1.
DR STRING; 6239.R06F6.6; -.
DR EPD; Q09602; -.
DR PaxDb; Q09602; -.
DR EnsemblMetazoa; R06F6.6.1; R06F6.6.1; WBGene00011069.
DR GeneID; 187642; -.
DR KEGG; cel:CELE_R06F6.6; -.
DR UCSC; R06F6.6; c. elegans.
DR CTD; 187642; -.
DR WormBase; R06F6.6; CE51240; WBGene00011069; ceh-62.
DR eggNOG; KOG0489; Eukaryota.
DR GeneTree; ENSGT00940000172642; -.
DR HOGENOM; CLU_660959_0_0_1; -.
DR InParanoid; Q09602; -.
DR OMA; HPYTRPI; -.
DR OrthoDB; 1260515at2759; -.
DR PRO; PR:Q09602; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00011069; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Homeobox; Nucleus; Reference proteome.
FT CHAIN 1..416
FT /note="Homeobox protein ceh-62"
FT /evidence="ECO:0000305"
FT /id="PRO_0000049399"
FT DNA_BIND 130..189
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 103..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..196
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 416 AA; 46455 MW; F162EAC580F4BB68 CRC64;
MHRKGGQTLR LYTHFLLHLS PHHHSFLDSI WQRKMVHPSS AFHPYTRPIP TTSGHDLPVD
DSLRLLLSAE ALIALAQLQD ASKILPSYEP VKDFSPQLLP AMTPTPIIAT PSIPEQPQPL
QSPSAPNEKS RRKRTTFSPE QATRLEAEYI GDSYMAREKR HLLAQSLKLS ENQVKTWFQN
RRAKDKRDRK SENASNHTSN SRRSSPSRKS SSDSTPTPTQ ATQFDMPTQI QTASPPTTAD
SAIFPPTSPE SIIQKIEQFP SNQILPNFDI LQTYLQSLSS SQIPLQFVPS TPPLFDPNML
QLYHVIFEFS QSETCSVSFQ RNSASNMRSL LIFVFFATIF AVDAQYDSAD SSQSEDLPDI
APESVSSEEI IEVDVNIEGS GSGDGPIIDQ VHMFGILPGP GDIRKKRGIL EILGRK
