ID   CELA_KOMXY              Reviewed;         284 AA.
AC   P27897;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=UTP--glucose-1-phosphate uridylyltransferase;
DE            EC=2.7.7.9;
DE   AltName: Full=Alpha-D-glucosyl-1-phosphate uridylyltransferase;
DE   AltName: Full=UDP-glucose pyrophosphorylase;
DE            Short=UDPGP;
DE   AltName: Full=Uridine diphosphoglucose pyrophosphorylase;
GN   Name=celA;
OS   Komagataeibacter xylinus (Gluconacetobacter xylinus).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Komagataeibacter.
OX   NCBI_TaxID=28448;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1938907; DOI=10.1128/jb.173.21.7042-7045.1991;
RA   Brede G., Fjaervik E., Valla S.;
RT   "Nucleotide sequence and expression analysis of the Acetobacter xylinum
RT   uridine diphosphoglucose pyrophosphorylase gene.";
RL   J. Bacteriol. 173:7042-7045(1991).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC         alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC         ChEBI:CHEBI:58885; EC=2.7.7.9;
CC   -!- SIMILARITY: Belongs to the UDPGP type 2 family. {ECO:0000305}.
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DR   EMBL; M76548; AAA21888.1; -; Genomic_DNA.
DR   PIR; A41382; A41382.
DR   AlphaFoldDB; P27897; -.
DR   SMR; P27897; -.
DR   GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR   CDD; cd02541; UGPase_prokaryotic; 1.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR43197; PTHR43197; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase; Transferase.
FT   CHAIN           1..284
FT                   /note="UTP--glucose-1-phosphate uridylyltransferase"
FT                   /id="PRO_0000201346"
SQ   SEQUENCE   284 AA;  30992 MW;  6C809AFFBBA1791B CRC64;
     MIKPLKKAVL PVAGLGTRFL PATKCVPKEM LTVVDRPLIQ YAIDEAREAG IEEFCLVSSR
     GKDSLIDYFD ISYELEDTLK ARKKTSALKA LEATRVIPGT MLSVPPAGTA GPWHAIWCAR
     EFIGNDPFAI LLPDDVVQSK KSCIGQLVEV YNKTGGNVLA VTEVPREQTG SYGILDVGKD
     DGKTVEVKGL VEKPDPKDAP STLSVIGRYV LTADVLKHLA KLEKGAGGEV QLTDAMAKTI
     GHVPFHGYRY EGKRFDCGSK IASWKPRSPL RWSVRNWLPA CVNS