ID   CELF5_XENTR             Reviewed;         486 AA.
AC   A0JM51;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=CUGBP Elav-like family member 5;
DE            Short=CELF-5;
DE   AltName: Full=Bruno-like protein 5;
DE   AltName: Full=CUG-BP- and ETR-3-like factor 5;
DE   AltName: Full=RNA-binding protein BRUNOL-5;
GN   Name=celf5; Synonyms=brunol5;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: RNA-binding protein that may be implicated in the regulation
CC       of pre-mRNA alternative splicing. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CELF/BRUNOL family. {ECO:0000305}.
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DR   EMBL; BC125739; AAI25740.1; -; mRNA.
DR   RefSeq; NP_001090639.1; NM_001097170.1.
DR   AlphaFoldDB; A0JM51; -.
DR   SMR; A0JM51; -.
DR   STRING; 8364.ENSXETP00000058992; -.
DR   PaxDb; A0JM51; -.
DR   DNASU; 100036604; -.
DR   GeneID; 100036604; -.
DR   KEGG; xtr:100036604; -.
DR   CTD; 60680; -.
DR   Xenbase; XB-GENE-494002; celf5.
DR   eggNOG; KOG0146; Eukaryota.
DR   InParanoid; A0JM51; -.
DR   OrthoDB; 1209165at2759; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000014344; Expressed in brain and 2 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0006376; P:mRNA splice site selection; IBA:GO_Central.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IBA:GO_Central.
DR   CDD; cd12632; RRM1_CELF3_4_5_6; 1.
DR   Gene3D; 3.30.70.330; -; 3.
DR   InterPro; IPR034648; CELF3/4/5/6_RRM1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 3.
DR   SMART; SM00360; RRM; 3.
DR   SUPFAM; SSF54928; SSF54928; 2.
DR   PROSITE; PS50102; RRM; 3.
PE   2: Evidence at transcript level;
KW   Cytoplasm; mRNA processing; Nucleus; Reference proteome; Repeat;
KW   RNA-binding.
FT   CHAIN           1..486
FT                   /note="CUGBP Elav-like family member 5"
FT                   /id="PRO_0000295228"
FT   DOMAIN          47..128
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          135..215
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          401..479
FT                   /note="RRM 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   486 AA;  52846 MW;  BF229DDF448C912B CRC64;
     MARLTEREAR RQQQQHPPQQ QQPRACPMSG PEPPAQQSDS MKDLDAIKLF VGQIPRNLEE
     KDLKPLFEQF GKIYELTVLK DRYTGMHKGC AFLTYCARDS AIKAQTALHE QKTLPGMARP
     IQVKPADSES RGGDRKLFVG MLSKQQSEEE VTSMFQAFGS IEECSVLRGP DGSSKGCAFV
     KFSSHAEAQA AIQALHGSQT MPGASSSLVV KFADTDKERT LRRMQQMVGQ LGIFTPSLAL
     PISPYSAYAQ ALMQQQTTVL STSHGSYLSP SVAFPSCHIQ QIGAVNLNGL PAAPITPASG
     LHSPPVIGTA AVPGLVAPLT NGFPGLVPFP SSHPALDTIY TNSIVPYPAQ SPALTVESLH
     PSFTGVQQYS AIYPTAALTP VTHSTPQPPP ILQQREGPEG CNLFIYHLPQ EFGDNELTQM
     FLPFGNIISS KVFMDRATNQ SKCFGFVSFD NPSSAQTAIQ AMNGFQIGMK RLKVQLKRPK
     DTTQPY