ID   CELL_ASPVE              Reviewed;           9 AA.
AC   C0HJH0;
DT   19-MAR-2014, integrated into UniProtKB/Swiss-Prot.
DT   19-MAR-2014, sequence version 1.
DT   12-AUG-2020, entry version 9.
DE   RecName: Full=Endo-beta-1,4-glucanase;
DE            Short=Endoglucanase;
DE            EC=3.2.1.4 {ECO:0000269|Ref.1};
DE   AltName: Full=Carboxymethylcellulase;
DE   AltName: Full=Cellulase {ECO:0000303|Ref.1};
DE   Flags: Fragment;
OS   Aspergillus versicolor.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=46472;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, CATALYTIC ACTIVITY, BIOPHYSICOCHEMICAL
RP   PROPERTIES, SUBCELLULAR LOCATION, AND INDUCTION.
RC   STRAIN=KIBGE-IB37 {ECO:0000269|Ref.1};
RA   Sofia Q., Sidra P., Faiza S., Afsheen A., Shah Ali Ul Q.;
RT   "Production, purification and characterization of cellulases from wild and
RT   mutant strains of Aspergillus versicolor KIBGE-IB37.";
RL   Submitted (DEC-2012) to UniProtKB.
CC   -!- FUNCTION: Has endoglucanase activity on substrates containing beta-1,4
CC       glycosidic bonds, like in carboxymethylcellulose (CMC).
CC       {ECO:0000269|Ref.1}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC         cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC         Evidence={ECO:0000269|Ref.1};
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       Kinetic parameters:
CC         KM=1.134 mM for carboxymethylcellulose {ECO:0000269|Ref.1};
CC       pH dependence:
CC         Optimum pH is 4.0. {ECO:0000269|Ref.1};
CC       Temperature dependence:
CC         Optimum temperature is 30 degrees Celsius. {ECO:0000269|Ref.1};
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC   -!- INDUCTION: Induced by Co(2+), Ba(2+), Mn(2+), Mg(2+) and Cu(2+) ions.
CC       Repressed by Hg(2+) ions and methanol. {ECO:0000269|Ref.1}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Carbohydrate metabolism; Cellulose degradation; Direct protein sequencing;
KW   Glycosidase; Hydrolase; Polysaccharide degradation; Secreted.
FT   CHAIN           1..>9
FT                   /note="Endo-beta-1,4-glucanase"
FT                   /id="PRO_0000425581"
FT   NON_TER         9
FT                   /evidence="ECO:0000303|Ref.1"
SQ   SEQUENCE   9 AA;  871 MW;  DFF932D1B6D05DDD CRC64;
     VAAIQTVLG