ID   CEMA_ADICA              Reviewed;         464 AA.
AC   Q85FL0;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 2.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Chloroplast envelope membrane protein;
GN   Name=cemA {ECO:0000255|HAMAP-Rule:MF_01308}; Synonyms=ycf10;
OS   Adiantum capillus-veneris (Maidenhair fern).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Polypodiopsida; Polypodiidae; Polypodiales; Pteridineae; Pteridaceae;
OC   Vittarioideae; Adiantum.
OX   NCBI_TaxID=13818;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12755170; DOI=10.1093/dnares/10.2.59;
RA   Wolf P.G., Rowe C.A., Sinclair R.B., Hasebe M.;
RT   "Complete nucleotide sequence of the chloroplast genome from a
RT   leptosporangiate fern, Adiantum capillus-veneris L.";
RL   DNA Res. 10:59-65(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND RNA EDITING.
RC   TISSUE=Frond;
RX   PubMed=15363849; DOI=10.1016/j.gene.2004.06.018;
RA   Wolf P.G., Rowe C.A., Hasebe M.;
RT   "High levels of RNA editing in a vascular plant chloroplast genome:
RT   analysis of transcripts from the fern Adiantum capillus-veneris.";
RL   Gene 339:89-97(2004).
CC   -!- FUNCTION: May be involved in proton extrusion. Indirectly promotes
CC       efficient inorganic carbon uptake into chloroplasts.
CC       {ECO:0000255|HAMAP-Rule:MF_01308}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01308}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01308}.
CC   -!- RNA EDITING: Modified_positions=303 {ECO:0000269|PubMed:15363849}, 333
CC       {ECO:0000269|PubMed:15363849}, 372 {ECO:0000269|PubMed:15363849}, 376
CC       {ECO:0000269|PubMed:15363849}, 427 {ECO:0000269|PubMed:15363849};
CC   -!- SIMILARITY: Belongs to the Cema family. {ECO:0000305}.
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DR   EMBL; AY178864; AAP29403.2; -; Genomic_DNA.
DR   RefSeq; NP_848072.2; NC_004766.1.
DR   AlphaFoldDB; Q85FL0; -.
DR   SMR; Q85FL0; -.
DR   GeneID; 807373; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01308; CemA; 1.
DR   InterPro; IPR004282; CemA.
DR   PANTHER; PTHR33650; PTHR33650; 1.
DR   Pfam; PF03040; CemA; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Hydrogen ion transport; Ion transport; Membrane; Plastid;
KW   Plastid inner membrane; RNA editing; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..464
FT                   /note="Chloroplast envelope membrane protein"
FT                   /id="PRO_0000216628"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        341..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
SQ   SEQUENCE   464 AA;  53857 MW;  78CFDC568ABA2C2D CRC64;
     MAAGNSSWAR AAFTFKATVF KKSRYVIYYS LLEHRFSLSL WGILKYSGIY FCTEILRSFP
     KKRCKSHPYR VDGYPAGSCL DPPLHEPLDT STPKKISLVS CSNSYMRNKT DNGKVGSRNV
     SEYKLEGDFA STSKSIYYKL NNLEKMNRKL AWIEAVSSEF SFWEKLRSKQ IFPFQNEKDL
     IAEPFNYELA VSHRRPVIYE SISLVPRSVT RTLSRFKAEL TNQSNLNLSV HNKFDLAKNQ
     ASVSLQYVGF LLFLFPIQIA IENWFLEPRI RGWWNIRQIQ LFSNVFQEEN ALKQLREAEA
     LFWLDDVIGN LADTQLQNFD TDARNETTRL AMMYDELNIQ LLLRLATNAI SIATLFPLLI
     FGRKRLAVLN SWIQELFYSL NDTMKAFSIL LLTDLCVGFH SPHGWEILVQ SLFEYFGLTP
     NKYVTPCFVS TFPVILDTLF KYWIFRHLNR TSPSIVATYH TMSE