ID   CEMA_ANTAG              Reviewed;         508 AA.
AC   Q85AP4;
DT   02-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Chloroplast envelope membrane protein;
GN   Name=cemA {ECO:0000255|HAMAP-Rule:MF_01308}; Synonyms=ycf10;
OS   Anthoceros angustus (Hornwort) (Anthoceros formosae).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Anthocerotophyta;
OC   Anthocerotopsida; Anthocerotidae; Anthocerotales; Anthocerotaceae;
OC   Anthoceros.
OX   NCBI_TaxID=48387;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND RNA EDITING.
RX   PubMed=12527781; DOI=10.1093/nar/gkg155;
RA   Kugita M., Kaneko A., Yamamoto Y., Takeya Y., Matsumoto T., Yoshinaga K.;
RT   "The complete nucleotide sequence of the hornwort (Anthoceros formosae)
RT   chloroplast genome: insight into the earliest land plants.";
RL   Nucleic Acids Res. 31:716-721(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND RNA EDITING.
RC   TISSUE=Thallus;
RX   PubMed=12711687; DOI=10.1093/nar/gkg327;
RA   Kugita M., Yamamoto Y., Fujikawa T., Matsumoto T., Yoshinaga K.;
RT   "RNA editing in hornwort chloroplasts makes more than half the genes
RT   functional.";
RL   Nucleic Acids Res. 31:2417-2423(2003).
CC   -!- FUNCTION: May be involved in proton extrusion. Indirectly promotes
CC       efficient inorganic carbon uptake into chloroplasts.
CC       {ECO:0000255|HAMAP-Rule:MF_01308}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01308}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01308}.
CC   -!- RNA EDITING: Modified_positions=9 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 91 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 121 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 251 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 252 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 268 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 299 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 324 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 434 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 445 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 457 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 480 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 489 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 492 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}, 498 {ECO:0000269|PubMed:12527781,
CC       ECO:0000269|PubMed:12711687}; Note=The nonsense codons at positions 268
CC       and 324 are modified to sense codons.;
CC   -!- SIMILARITY: Belongs to the Cema family. {ECO:0000305}.
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DR   EMBL; AB086179; BAC55361.1; -; Genomic_DNA.
DR   EMBL; AB087453; BAC55457.1; -; mRNA.
DR   RefSeq; NP_777425.1; NC_004543.1.
DR   AlphaFoldDB; Q85AP4; -.
DR   SMR; Q85AP4; -.
DR   GeneID; 2553517; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01308; CemA; 1.
DR   InterPro; IPR004282; CemA.
DR   PANTHER; PTHR33650; PTHR33650; 1.
DR   Pfam; PF03040; CemA; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Hydrogen ion transport; Ion transport; Membrane; Plastid;
KW   Plastid inner membrane; RNA editing; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..508
FT                   /note="Chloroplast envelope membrane protein"
FT                   /id="PRO_0000216632"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        386..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        433..453
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        468..488
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
SQ   SEQUENCE   508 AA;  60285 MW;  BF6F35EBE19D5A89 CRC64;
     MKLYQWQIFR WFFETLNCSL GRAYKASKRI QYIKKDYSFY KNTILFSKGS WQAINLYTNT
     ELRNTLFIIY WSLLEYRISL CFLNLLRKIE SIQFKKLSVI SFILNLHSSL SHVNKQLQIL
     SKVLFDRFYF YLWKNMYFSL LLHNSLSRFV KESIEESEQS GFNNENKKDF QDETYFVLNE
     SLEKDFSRIR EMNRKLAWIE VTLNDLNTWK SYYLFFPFLS EMKNTPQNES SFKLKNFEIT
     TPAYDSTGFI PRSISRTLSR FQIELMGQSS SLVLQEFRSA KYQALASIQY IGCLIFLPWI
     ISRSLKEWFL EPWIKFWWDT YQSQISLNSF QEERASEGLQ EVEEPLWLDK LVSNFLKNQS
     QDLNIEIYGE TIQLIRMYNE NSIQTILHLL TGMICFTTLG ALFILGKKRL SVLNSWIQES
     FYSLSDTMKA FAILLLTDLC IGFHSPHGWE VVIGSSLEHL GFAHNKHIIS CFVSTFPVIL
     DTVSKYWIFR HLNRISPSIV ATYHTMNE