ID   CEMA_GUITH              Reviewed;         278 AA.
AC   O78470;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Chloroplast envelope membrane protein;
GN   Name=cemA {ECO:0000255|HAMAP-Rule:MF_01308}; Synonyms=ycf10;
OS   Guillardia theta (Cryptophyte) (Cryptomonas phi).
OG   Plastid; Chloroplast.
OC   Eukaryota; Cryptophyceae; Pyrenomonadales; Geminigeraceae; Guillardia.
OX   NCBI_TaxID=55529;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9929392; DOI=10.1007/pl00006462;
RA   Douglas S.E., Penny S.L.;
RT   "The plastid genome of the cryptophyte alga, Guillardia theta: complete
RT   sequence and conserved synteny groups confirm its common ancestry with red
RT   algae.";
RL   J. Mol. Evol. 48:236-244(1999).
CC   -!- FUNCTION: May be involved in proton extrusion. Indirectly promotes
CC       efficient inorganic carbon uptake into chloroplasts.
CC       {ECO:0000255|HAMAP-Rule:MF_01308}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01308}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01308}.
CC   -!- SIMILARITY: Belongs to the Cema family. {ECO:0000305}.
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DR   EMBL; AF041468; AAC35661.1; -; Genomic_DNA.
DR   RefSeq; NP_050727.1; NC_000926.1.
DR   AlphaFoldDB; O78470; -.
DR   SMR; O78470; -.
DR   GeneID; 857031; -.
DR   HOGENOM; CLU_1002709_0_0_1; -.
DR   OMA; HSPEGWT; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01308; CemA; 1.
DR   InterPro; IPR004282; CemA.
DR   PANTHER; PTHR33650; PTHR33650; 1.
DR   Pfam; PF03040; CemA; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Hydrogen ion transport; Ion transport; Membrane; Plastid;
KW   Plastid inner membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..278
FT                   /note="Chloroplast envelope membrane protein"
FT                   /id="PRO_0000216643"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        239..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
SQ   SEQUENCE   278 AA;  32209 MW;  1E78817DC25582DE CRC64;
     MKNWRLNNVT ESAFEKTGPI PRSIAKTFEK FKKELEPNSE SEIIEEFRVS RYQTASSIKY
     LVLLVTVPLL INQASKSLVF SPFIDYFWND NQSDIFLNES QEERAFSELQ RFEEKIHFEI
     LIGQSPPLSQ ETIDKEIKNK AIELAQFYVQ ESTDAIKNLL ADILAFITFA YLIFTGGRQI
     AVLKSFINEL IYGLSDTAKA FLIILFTDIF VGFHSTHGWE VVLENGLRHF GLPENRDLIF
     LFIATFPVVL DTVFKYWIFR YLNQVSPSAV ATYHEMNE