ID   CEMA_MANES              Reviewed;         231 AA.
AC   B1NWG2;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Chloroplast envelope membrane protein;
GN   Name=cemA {ECO:0000255|HAMAP-Rule:MF_01308};
OS   Manihot esculenta (Cassava) (Jatropha manihot).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC   Manihot.
OX   NCBI_TaxID=3983;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TME3;
RX   PubMed=18214421; DOI=10.1007/s00122-007-0706-y;
RA   Daniell H., Wurdack K.J., Kanagaraj A., Lee S.-B., Saski C., Jansen R.K.;
RT   "The complete nucleotide sequence of the cassava (Manihot esculenta)
RT   chloroplast genome and the evolution of atpF in Malpighiales: RNA editing
RT   and multiple losses of a group II intron.";
RL   Theor. Appl. Genet. 116:723-737(2008).
CC   -!- FUNCTION: May be involved in proton extrusion. Indirectly promotes
CC       efficient inorganic carbon uptake into chloroplasts.
CC       {ECO:0000255|HAMAP-Rule:MF_01308}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01308}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01308}.
CC   -!- SIMILARITY: Belongs to the Cema family. {ECO:0000305}.
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DR   EMBL; EU117376; ABV66166.1; -; Genomic_DNA.
DR   RefSeq; YP_001718449.1; NC_010433.1.
DR   AlphaFoldDB; B1NWG2; -.
DR   GeneID; 6000061; -.
DR   KEGG; mesc:6000061; -.
DR   OrthoDB; 1276845at2759; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01308; CemA; 1.
DR   InterPro; IPR004282; CemA.
DR   PANTHER; PTHR33650; PTHR33650; 1.
DR   Pfam; PF03040; CemA; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Hydrogen ion transport; Ion transport; Membrane; Plastid;
KW   Plastid inner membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..231
FT                   /note="Chloroplast envelope membrane protein"
FT                   /id="PRO_0000346543"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
SQ   SEQUENCE   231 AA;  27307 MW;  A1A564A49969A7B2 CRC64;
     MKKWKKKTFI PLLYLTSIVF LPWWVSFLFN KSLESWIINC CNTSKSETFL NDIQEKSILE
     KFMELEDLVR LNEIIKEYPE THLQKFRIGI HKETIQLIKM HNEDRIHTIL HFSTNIICFI
     ILSGYSILSN EELIILNSWV QEFLYNLSDT IKAFSILLLT DLCIGFHSPH GWELMIGSVY
     KDFGFAHNDQ IISGLVSTFP VILDTIFKYW IFRYLNRVSP SLVVIYHSMN D