ID   CEMA_NICTO              Reviewed;         229 AA.
AC   Q33C21;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Chloroplast envelope membrane protein;
GN   Name=cemA {ECO:0000255|HAMAP-Rule:MF_01308};
OS   Nicotiana tomentosiformis (Tobacco).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4098;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16435119; DOI=10.1007/s00438-005-0092-6;
RA   Yukawa M., Tsudzuki T., Sugiura M.;
RT   "The chloroplast genome of Nicotiana sylvestris and Nicotiana
RT   tomentosiformis: complete sequencing confirms that the Nicotiana sylvestris
RT   progenitor is the maternal genome donor of Nicotiana tabacum.";
RL   Mol. Genet. Genomics 275:367-373(2006).
CC   -!- FUNCTION: May be involved in proton extrusion. Indirectly promotes
CC       efficient inorganic carbon uptake into chloroplasts.
CC       {ECO:0000255|HAMAP-Rule:MF_01308}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01308}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01308}.
CC   -!- SIMILARITY: Belongs to the Cema family. {ECO:0000305}.
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DR   EMBL; AB240139; BAE48014.1; -; Genomic_DNA.
DR   RefSeq; YP_398876.1; NC_007602.1.
DR   AlphaFoldDB; Q33C21; -.
DR   GeneID; 3776314; -.
DR   KEGG; nto:3776314; -.
DR   OrthoDB; 1276845at2759; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01308; CemA; 1.
DR   InterPro; IPR004282; CemA.
DR   PANTHER; PTHR33650; PTHR33650; 1.
DR   Pfam; PF03040; CemA; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Hydrogen ion transport; Ion transport; Membrane; Plastid;
KW   Plastid inner membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..229
FT                   /note="Chloroplast envelope membrane protein"
FT                   /id="PRO_0000275246"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        189..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
SQ   SEQUENCE   229 AA;  26745 MW;  C4607C51391CC551 CRC64;
     MAKKKAFTPL FYLASIVFLP WWISFSVNKC LESWVTNWWN TGQSEIFLNN IQEKSLLEKF
     IELEELLFLD EMVKEYSETH LEEFGIGIHK ETIQLIKIQN ENRIHTILHF STNIICFIIL
     SGYSILGNEN LAILNSWAQE FLYNLSDTVK AFSILLLTDL CIGFHSPHGW ELMIGSIYKD
     FGFVHSDQII SGLVSTFPVI LDTIFKYWIF RYLNRLSPSL VVIYHSMND