ID   CEMA_SYNY3              Reviewed;         393 AA.
AC   P72771; Q55099;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 123.
DE   RecName: Full=CemA-like protein sll1685;
GN   OrderedLocusNames=sll1685;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8663186; DOI=10.1074/jbc.271.28.16662;
RA   Jensen P.E., Gibson L.C.D., Henningsen K.W., Hunter C.N.;
RT   "Expression of the chlI, chlD, and chlH genes from the Cyanobacterium
RT   synechocystis PCC6803 in Escherichia coli and demonstration that the three
RT   cognate proteins are required for magnesium-protoporphyrin chelatase
RT   activity.";
RL   J. Biol. Chem. 271:16662-16667(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: May be involved in proton extrusion. Indirectly promotes
CC       efficient inorganic carbon uptake (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the Cema family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X96599; CAA65417.1; -; Genomic_DNA.
DR   EMBL; BA000022; BAA16786.1; -; Genomic_DNA.
DR   PIR; S74634; S74634.
DR   PIR; T46869; T46869.
DR   AlphaFoldDB; P72771; -.
DR   SMR; P72771; -.
DR   IntAct; P72771; 2.
DR   STRING; 1148.1651859; -.
DR   PaxDb; P72771; -.
DR   EnsemblBacteria; BAA16786; BAA16786; BAA16786.
DR   KEGG; syn:sll1685; -.
DR   eggNOG; ENOG502Z8DN; Bacteria.
DR   InParanoid; P72771; -.
DR   OMA; GHESEEN; -.
DR   PhylomeDB; P72771; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01308; CemA; 1.
DR   InterPro; IPR004282; CemA.
DR   PANTHER; PTHR33650; PTHR33650; 1.
DR   Pfam; PF03040; CemA; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Hydrogen ion transport; Ion transport;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..393
FT                   /note="CemA-like protein sll1685"
FT                   /id="PRO_0000216667"
FT   TRANSMEM        169..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        306..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        352..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        45..46
FT                   /note="DG -> GR (in Ref. 1; CAA65417)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        139
FT                   /note="S -> G (in Ref. 1; CAA65417)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        194
FT                   /note="A -> G (in Ref. 1; CAA65417)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   393 AA;  45466 MW;  A83C3DEC2AB8FB12 CRC64;
     MLPDKKLGSP NHRFHHWLVR QAIAALDNAQ VSAQAIESIE KTYFDGGKIA PDSQRGVNTY
     NYFKSTLERE LLKIKFNLAR FNATNLLNNS EDFQITEAEI IVKLDAIEKI IAKYRFSEDL
     VEVDSQSSAE INNISPKRSN FFNIQRDLSA QDEQKILQNL RNLRLQRRIA TRFLIVLIFI
     PLTVQILTKN LVFAPLVQHF RVDIVAWEKI HYQEETIEHY FEEFARYKET LEIKQLLSEN
     QPLNQEKIHQ ELKKKAEELI RQAATNSQQG IVNLLADIAG LVAFVVLIIV FRGKSIITQQ
     YLSQSFLALN DITKVFIFIL LTDMFVGFHS AHGWEVVLEN LTSHFGLPEN RHAVYIFIAT
     VPVFLDSLFK LLIFNYFTRQ SPTSVAILEK MQQ