ID   CEMA_WELMI              Reviewed;         259 AA.
AC   B2Y1X1;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=envelope membrane protein, chloroplastic {ECO:0000255|HAMAP-Rule:MF_01308};
GN   Name=cemA {ECO:0000255|HAMAP-Rule:MF_01308};
OS   Welwitschia mirabilis (Tree tumbo) (Welwitschia bainesii).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Gnetopsida; Gnetidae; Welwitschiales; Welwitschiaceae;
OC   Welwitschia.
OX   NCBI_TaxID=3377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18452621; DOI=10.1186/1471-2148-8-130;
RA   McCoy S.R., Kuehl J.V., Boore J.L., Raubeson L.A.;
RT   "The complete plastid genome sequence of Welwitschia mirabilis: an
RT   unusually compact plastome with accelerated divergence rates.";
RL   BMC Evol. Biol. 8:130-130(2008).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=19166950; DOI=10.1016/j.ympev.2008.12.026;
RA   Wu C.-S., Lai Y.-T., Lin C.-P., Wang Y.-N., Chaw S.-M.;
RT   "Evolution of reduced and compact chloroplast genomes (cpDNAs) in
RT   gnetophytes: Selection toward a lower-cost strategy.";
RL   Mol. Phylogenet. Evol. 52:115-124(2009).
CC   -!- FUNCTION: May be involved in proton extrusion. Indirectly promotes
CC       efficient inorganic carbon uptake into chloroplasts.
CC       {ECO:0000255|HAMAP-Rule:MF_01308}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01308}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01308}.
CC   -!- SIMILARITY: Belongs to the Cema family. {ECO:0000305}.
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DR   EMBL; EU342371; ABY26801.1; -; Genomic_DNA.
DR   EMBL; AP009568; BAH11217.1; -; Genomic_DNA.
DR   RefSeq; YP_001876588.1; NC_010654.1.
DR   AlphaFoldDB; B2Y1X1; -.
DR   GeneID; 6276227; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01308; CemA; 1.
DR   InterPro; IPR004282; CemA.
DR   PANTHER; PTHR33650; PTHR33650; 1.
DR   Pfam; PF03040; CemA; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Hydrogen ion transport; Ion transport; Membrane; Plastid;
KW   Plastid inner membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..259
FT                   /note="envelope membrane protein, chloroplastic"
FT                   /id="PRO_1000165469"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        184..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
SQ   SEQUENCE   259 AA;  30522 MW;  6FF8710070650C89 CRC64;
     MGLIPHSIIR TLSRLRTEFM SKSGPLVFYE MEVAKKRASA SLRYLTCLLV LPWVISILLQ
     KSIEPWVTFW WNTSSFDILD FLEEENTLVI FGQIEELLLF ERMIENYSET YSKPSSKEIK
     KKTNVIKLYK KDCIHIITHL FTNFIGFALL STYLVMGQKK LAIFFSWIRE FFYSMSDTMK
     AFSILLATDL CIGFHSPHGW ELLIDWISEN YGFVHNDRII SSLVSTFPVI LDTIFKYWIF
     RRFNRISPSL VVIYHSMNE