ID   CENNA_XENLA             Reviewed;         348 AA.
AC   Q5XH29;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 2.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Centromere protein N-A;
DE            Short=CENP-N-A;
GN   Name=cenpn-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable component of a centromeric complex involved in
CC       assembly of kinetochore proteins, mitotic progression and chromosome
CC       segregation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome, centromere
CC       {ECO:0000250}. Note=Localizes exclusively in the centromeres.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CENP-N/CHL4 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH84246.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BC084246; AAH84246.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001088250.1; NM_001094781.1.
DR   AlphaFoldDB; Q5XH29; -.
DR   SMR; Q5XH29; -.
DR   DNASU; 495081; -.
DR   GeneID; 495081; -.
DR   KEGG; xla:495081; -.
DR   CTD; 495081; -.
DR   Xenbase; XB-GENE-6077945; cenpn.S.
DR   OrthoDB; 1145159at2759; -.
DR   Proteomes; UP000186698; Chromosome 4S.
DR   Bgee; 495081; Expressed in egg cell and 15 other tissues.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007059; P:chromosome segregation; IEA:InterPro.
DR   GO; GO:0051382; P:kinetochore assembly; IEA:InterPro.
DR   InterPro; IPR007902; Chl4/mis15/CENP-N.
DR   Pfam; PF05238; CENP-N; 1.
PE   2: Evidence at transcript level;
KW   Centromere; Chromosome; Nucleus; Reference proteome.
FT   CHAIN           1..348
FT                   /note="Centromere protein N-A"
FT                   /id="PRO_0000249498"
SQ   SEQUENCE   348 AA;  39729 MW;  8EB9DD1AF6423820 CRC64;
     MDEWLAEFIK RTILKLPFSE TVTILKAWGF LTESELQTFT FRYPKDVTAT EVVRLCEAKN
     ATVDHAAALD LVFNHAYSNK KSWTVYQMSK PSESENDLFD ASEFKLQFKK SIHAVSKNVT
     LNFKQFGEAL WIRIAWGTHN TRPNQYKATF AVYHSQTPYV FITGLGKACR PLMCQALVIA
     AKYSQIQEME LKSRCLESLK DIVFKRFNQP FSSHHSIPHE KALIPKIVDP RVIYENMREK
     DRVSHLTRET FGEGPLPKLE LASYKLETMF RAESIMDGNL TAVNEPFRCV VKFSSPHLLE
     AIRSLAPAGI AEAPISTLLS CIPHKARNSF KITEKRGMHP TSSQTTNF