ID   CENPQ_CHICK             Reviewed;         283 AA.
AC   Q1T764;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Centromere protein Q;
DE            Short=CENP-Q;
GN   Name=CENPQ;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16622420; DOI=10.1038/ncb1396;
RA   Okada M., Cheeseman I.M., Hori T., Okawa K., McLeod I.X., Yates J.R. III,
RA   Desai A., Fukagawa T.;
RT   "The CENP-H-I complex is required for the efficient incorporation of newly
RT   synthesized CENP-A into centromeres.";
RL   Nat. Cell Biol. 8:446-457(2006).
CC   -!- FUNCTION: Probable component of a centromeric complex involved in
CC       assembly of kinetochore proteins, mitotic progression and chromosome
CC       segregation. May play an important role in chromosome congression and
CC       in the recruitment of CENP-O complex (which comprises CENPO, CENPP,
CC       CENPQ and CENPU), CENPE and PLK1 to the kinetochores.
CC       {ECO:0000250|UniProtKB:Q7L2Z9}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q7L2Z9}.
CC       Chromosome, centromere {ECO:0000250|UniProtKB:Q7L2Z9}. Note=Localizes
CC       exclusively in the centromeres. {ECO:0000250|UniProtKB:Q7L2Z9}.
CC   -!- SIMILARITY: Belongs to the CENP-Q/OKP1 family. {ECO:0000305}.
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DR   EMBL; AB253770; BAE93422.1; -; mRNA.
DR   RefSeq; NP_001038114.1; NM_001044649.1.
DR   AlphaFoldDB; Q1T764; -.
DR   SMR; Q1T764; -.
DR   STRING; 9031.ENSGALP00000035912; -.
DR   PaxDb; Q1T764; -.
DR   GeneID; 422048; -.
DR   KEGG; gga:422048; -.
DR   CTD; 55166; -.
DR   VEuPathDB; HostDB:geneid_422048; -.
DR   eggNOG; ENOG502S34R; Eukaryota.
DR   InParanoid; Q1T764; -.
DR   OrthoDB; 1159538at2759; -.
DR   PhylomeDB; Q1T764; -.
DR   PRO; PR:Q1T764; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0051310; P:metaphase plate congression; ISS:UniProtKB.
DR   GO; GO:1905342; P:positive regulation of protein localization to kinetochore; ISS:UniProtKB.
DR   InterPro; IPR025212; CAD_CENP-Q.
DR   PANTHER; PTHR31345; PTHR31345; 1.
DR   Pfam; PF13094; CENP-Q; 1.
PE   2: Evidence at transcript level;
KW   Centromere; Chromosome; Coiled coil; Nucleus; Reference proteome.
FT   CHAIN           1..283
FT                   /note="Centromere protein Q"
FT                   /id="PRO_0000249511"
FT   REGION          1..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          159..224
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        8..23
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..82
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   283 AA;  32203 MW;  8BF52AA13F03A800 CRC64;
     MKRHRASSGK RGETADGGRV KRPTKSHNQQ GPTSQKRGTV GKGDKRAQKR KLVTQAVRRE
     DEEHEDSSSA GEKGHSKKVK LSSAKVESWQ PLSESSRKFL ESVMDSGILS ILCQQSKGKE
     DVQKHLNLLK ERVLRVFKTL KVPLGKLSNL NNVLSFQVAQ KQMLEMNETA LVQLQEEINE
     AEKSAERTEE TILRLQHDIQ VLKSQLEEEE KKARKLCREG DTKELHLPEL PKCSLQAPTL
     QEEILMVKNQ KGLLEDMNTI QQSADMRNML TFIEKIYEKV DLV