ID   CEN_ANTMA               Reviewed;         181 AA.
AC   Q41261; Q9FPC9; Q9FPD0;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Protein CENTRORADIALIS;
GN   Name=CEN;
OS   Antirrhinum majus (Garden snapdragon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Lamiales; Plantaginaceae; Antirrhineae; Antirrhinum.
OX   NCBI_TaxID=4151;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8587601; DOI=10.1038/379791a0;
RA   Bradley D., Carpenter R., Copsey L., Vincent C., Rothstein S., Coen E.S.;
RT   "Control of inflorescence architecture in Antirrhinum.";
RL   Nature 379:791-797(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. 164, and cv. Snowman;
RX   PubMed=11457954; DOI=10.1104/pp.126.3.1031;
RA   Cremer F., Loennig W.E., Saedler H., Huijser P.;
RT   "The delayed terminal flower phenotype is caused by a conditional mutation
RT   in the CENTRORADIALIS gene of snapdragon.";
RL   Plant Physiol. 126:1031-1041(2001).
RN   [3]
RP   X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS).
RX   PubMed=10764580; DOI=10.1006/jmbi.2000.3619;
RA   Banfield M.J., Brady R.L.;
RT   "The structure of antirrhinum centroradialis protein (CEN) suggests a role
RT   as a kinase regulator.";
RL   J. Mol. Biol. 297:1159-1170(2000).
CC   -!- FUNCTION: Expression of CEN leads to a morphological switch between
CC       shoot growth and the development of flower structures (inflorescence).
CC       May form complexes with phosphorylated ligands by interfering with
CC       kinases and their effectors.
CC   -!- SUBUNIT: May form homodimers in solution.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the phosphatidylethanolamine-binding protein
CC       family. {ECO:0000305}.
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DR   EMBL; S81193; AAB36112.1; -; mRNA.
DR   EMBL; AJ251993; CAC21563.1; -; Genomic_DNA.
DR   EMBL; AJ251994; CAC21564.1; -; Genomic_DNA.
DR   PIR; S68507; S68507.
DR   PDB; 1QOU; X-ray; 1.90 A; A/B=1-181.
DR   PDBsum; 1QOU; -.
DR   AlphaFoldDB; Q41261; -.
DR   SMR; Q41261; -.
DR   EvolutionaryTrace; Q41261; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR   CDD; cd00866; PEBP_euk; 1.
DR   Gene3D; 3.90.280.10; -; 1.
DR   InterPro; IPR008914; PEBP.
DR   InterPro; IPR036610; PEBP-like_sf.
DR   InterPro; IPR035810; PEBP_euk.
DR   InterPro; IPR001858; Phosphatidylethanolamine-bd_CS.
DR   PANTHER; PTHR11362; PTHR11362; 1.
DR   Pfam; PF01161; PBP; 1.
DR   SUPFAM; SSF49777; SSF49777; 1.
DR   PROSITE; PS01220; PBP; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; Developmental protein; Differentiation; Flowering.
FT   CHAIN           1..181
FT                   /note="Protein CENTRORADIALIS"
FT                   /id="PRO_0000204755"
FT   VARIANT         5
FT                   /note="V -> I (in strain: cv. 164 and cv. Snowman)"
FT   VARIANT         28
FT                   /note="K -> Q (in strain: cv. Snowman)"
FT   VARIANT         35
FT                   /note="S -> A (in strain: cv. 164 and cv. Snowman)"
FT   HELIX           9..12
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   TURN            17..19
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   STRAND          29..33
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   HELIX           50..52
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   STRAND          53..55
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   STRAND          58..61
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   STRAND          69..76
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   STRAND          82..84
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   STRAND          90..99
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   HELIX           104..106
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   STRAND          107..111
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   STRAND          123..131
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   HELIX           152..158
FT                   /evidence="ECO:0007829|PDB:1QOU"
FT   STRAND          165..172
FT                   /evidence="ECO:0007829|PDB:1QOU"
SQ   SEQUENCE   181 AA;  20322 MW;  32673415FE29E503 CRC64;
     MAAKVSSDPL VIGRVIGDVV DHFTSTVKMS VIYNSNNSIK HVYNGHELFP SAVTSTPRVE
     VHGGDMRSFF TLIMTDPDVP GPSDPYLREH LHWIVTDIPG TTDSSFGKEV VSYEMPRPNI
     GIHRFVFLLF KQKKRGQAML SPPVVCRDGF NTRKFTQENE LGLPVAAVFF NCQRETAARR
     R