ID   CEP1_EBVG               Reviewed;         278 AA.
AC   Q3KSR8;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   23-FEB-2022, entry version 35.
DE   RecName: Full=Cytoplasmic envelopment protein 1 {ECO:0000255|HAMAP-Rule:MF_04038};
GN   ORFNames=BBRF2;
OS   Epstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Lymphocryptovirus.
OX   NCBI_TaxID=10376;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16306603; DOI=10.1128/jvi.79.24.15323-15330.2005;
RA   Zeng M.-S., Li D.-J., Liu Q.-L., Song L.-B., Li M.-Z., Zhang R.-H.,
RA   Yu X.-J., Wang H.-M., Ernberg I., Zeng Y.-X.;
RT   "Genomic sequence analysis of Epstein-Barr virus strain GD1 from a
RT   nasopharyngeal carcinoma patient.";
RL   J. Virol. 79:15323-15330(2005).
CC   -!- FUNCTION: Plays a critical role in cytoplasmic virus egress.
CC       Participates in the final step of tegumentation and envelope
CC       acquisition within the host cytoplasm. {ECO:0000255|HAMAP-
CC       Rule:MF_04038}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04038}. Virion
CC       tegument {ECO:0000255|HAMAP-Rule:MF_04038}. Host cytoplasm
CC       {ECO:0000255|HAMAP-Rule:MF_04038}. Host Golgi apparatus
CC       {ECO:0000255|HAMAP-Rule:MF_04038}.
CC   -!- SIMILARITY: Belongs to the herpesviridae cytoplasmic envelopment
CC       protein 1 family. {ECO:0000255|HAMAP-Rule:MF_04038}.
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DR   EMBL; AY961628; AAY41131.1; -; Genomic_DNA.
DR   PDB; 6LQN; X-ray; 1.60 A; A=17-278.
DR   PDB; 6LQO; X-ray; 3.09 A; A/B/C/D/E/F=17-278.
DR   PDBsum; 6LQN; -.
DR   PDBsum; 6LQO; -.
DR   SMR; Q3KSR8; -.
DR   IntAct; Q3KSR8; 4.
DR   MINT; Q3KSR8; -.
DR   Proteomes; UP000007641; Genome.
DR   GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_04038; HSV_CEP1; 1.
DR   InterPro; IPR002600; Herpes_UL7.
DR   Pfam; PF01677; Herpes_UL7; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Host cytoplasm; Host Golgi apparatus; Virion;
KW   Virion tegument.
FT   CHAIN           1..278
FT                   /note="Cytoplasmic envelopment protein 1"
FT                   /id="PRO_0000375976"
FT   TURN            17..19
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   STRAND          24..35
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   STRAND          38..42
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   HELIX           56..68
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   STRAND          70..81
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   HELIX           82..84
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   STRAND          87..90
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   HELIX           94..100
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   STRAND          101..104
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   HELIX           109..123
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   HELIX           129..146
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   HELIX           149..168
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   HELIX           186..194
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   HELIX           199..209
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   HELIX           213..215
FT                   /evidence="ECO:0007829|PDB:6LQO"
FT   HELIX           222..234
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   TURN            235..237
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   STRAND          240..244
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   HELIX           252..255
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   HELIX           257..268
FT                   /evidence="ECO:0007829|PDB:6LQN"
FT   STRAND          272..274
FT                   /evidence="ECO:0007829|PDB:6LQN"
SQ   SEQUENCE   278 AA;  31272 MW;  A48079C6B8A94C08 CRC64;
     MASGKHHQPG GTRSLTMQKV SLRVTPRLVL EVNRHNAICV ATNVPEFYNA RGDLNVRDLR
     AHVKARMISS QFCGYILVSL LDSEDQVDHL NIFPHVFSER MILYKPNNVN LMEMCALLSM
     IENAKSPSIG LCREVLGRLT LLHSKCNNLD SLFLYNGART LLSTLVKYHD LEEGAATPGP
     WNEGLSLFKL HKELKRAPSE ARDLMQSLFL TSGKMGCLAR SPKDYCADLN KEEDANSGFT
     FNLFYQDSLL TKHFQCQTVL QTLRRKCLGS DTVSKIIP