ID   CEP20_CHICK             Reviewed;         175 AA.
AC   Q5ZJ24;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Centrosomal protein 20 {ECO:0000305};
DE   AltName: Full=FGFR1OP N-terminal-like protein;
DE   AltName: Full=LisH domain-containing protein FOPNL;
GN   Name=CEP20; Synonyms=FOPNL; ORFNames=RCJMB04_21j4;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Involved in the biogenesis of cilia (By similarity). Required
CC       for the recruitment of PLK1 to centrosomes and S phase progression (By
CC       similarity). {ECO:0000250|UniProtKB:Q96NB1}.
CC   -!- SUBUNIT: Homooligomer; probably required for localization to
CC       centrosomes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000250}. Cytoplasm,
CC       cytoskeleton, cilium basal body {ECO:0000250}. Cytoplasm, cytoskeleton,
CC       microtubule organizing center, centrosome {ECO:0000250}. Cytoplasmic
CC       granule {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome, centriolar satellite {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CEP43 family. {ECO:0000305}.
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DR   EMBL; AJ720610; CAG32269.1; -; mRNA.
DR   RefSeq; NP_001006170.1; NM_001006170.1.
DR   AlphaFoldDB; Q5ZJ24; -.
DR   SMR; Q5ZJ24; -.
DR   STRING; 9031.ENSGALP00000010542; -.
DR   PaxDb; Q5ZJ24; -.
DR   GeneID; 416598; -.
DR   KEGG; gga:416598; -.
DR   CTD; 416598; -.
DR   VEuPathDB; HostDB:geneid_416598; -.
DR   eggNOG; ENOG502S0C1; Eukaryota.
DR   InParanoid; Q5ZJ24; -.
DR   OrthoDB; 1472201at2759; -.
DR   PhylomeDB; Q5ZJ24; -.
DR   PRO; PR:Q5ZJ24; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0034451; C:centriolar satellite; ISS:UniProtKB.
DR   GO; GO:0005813; C:centrosome; IBA:GO_Central.
DR   GO; GO:0036064; C:ciliary basal body; ISS:UniProtKB.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0031514; C:motile cilium; ISS:UniProtKB.
DR   GO; GO:0060271; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0034453; P:microtubule anchoring; IEA:InterPro.
DR   InterPro; IPR018993; FOP_dimerisation-dom_N.
DR   InterPro; IPR006594; LisH.
DR   Pfam; PF09398; FOP_dimer; 1.
DR   SMART; SM00667; LisH; 1.
DR   PROSITE; PS50896; LISH; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium biogenesis/degradation; Cytoplasm; Cytoskeleton;
KW   Reference proteome.
FT   CHAIN           1..175
FT                   /note="Centrosomal protein 20"
FT                   /id="PRO_0000264467"
FT   DOMAIN          49..81
FT                   /note="LisH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00126"
FT   REGION          1..104
FT                   /note="Necessary and sufficient for homooligomerization and
FT                   localization to centrosomes and pericentriolar satellites"
FT                   /evidence="ECO:0000250"
FT   REGION          137..166
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   175 AA;  19830 MW;  D94C0870A40C1AAA CRC64;
     MATIAELKAV LKDTLEKRGA LRQIKARIRA EVFNALDDQS EPRPPLCHEN LLINELIREY
     LEFNKYKYSA SVLTAEAGQP EVPLDRQFLV KELNIVEDAN GKSVPLLYGI ISHFLHRGKE
     ESTQSTLPKV SLLSYPRQNL AKPSTERNQK DRIPEPGRMA GTSIEEPLVL QSIKR