ID   CEP_VIBCH               Reviewed;          82 AA.
AC   Q9K323;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Colonization factor;
DE   Flags: Precursor;
GN   Name=cep; OrderedLocusNames=VC_1461;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 55056 / El Tor Ogawa E7946;
RX   PubMed=8475125; DOI=10.1073/pnas.90.8.3750;
RA   Pearson G.D., Woods A., Chiang S.L., Mekalanos J.J.;
RT   "CTX genetic element encodes a site-specific recombination system and an
RT   intestinal colonization factor.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:3750-3754(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=El Tor 86015 / Serotype O1;
RA   Kan B., Liu Y.Q., Qi G.M., Gao S.Y.;
RT   "Vibrio cholerae nct-CTXphi whole genome, include rstR(RstR), rstA(RstA),
RT   rstB(RstB), cep(Cep), orfU(OrfU), ace(Ace) and zot(Zot) genes.";
RL   Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR   EMBL; AE003852; AAF94618.1; -; Genomic_DNA.
DR   EMBL; AF220606; AAF29544.1; -; Genomic_DNA.
DR   PIR; A47482; A47482.
DR   RefSeq; NP_231104.1; NC_002505.1.
DR   RefSeq; WP_000493022.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9K323; -.
DR   STRING; 243277.VC_1461; -.
DR   DNASU; 2613967; -.
DR   EnsemblBacteria; AAF94618; AAF94618; VC_1461.
DR   GeneID; 57740124; -.
DR   KEGG; vch:VC_1461; -.
DR   PATRIC; fig|243277.26.peg.1391; -.
DR   HOGENOM; CLU_2557358_0_0_6; -.
DR   BioCyc; VCHO:VC1461-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..33
FT                   /evidence="ECO:0000255"
FT   CHAIN           34..82
FT                   /note="Colonization factor"
FT                   /id="PRO_0000020922"
SQ   SEQUENCE   82 AA;  8480 MW;  54ADC8D935E45C13 CRC64;
     MFSSLKNKLN TFKSTLSLGV FLLFSAFANQ ALAAADAGLV TEVTKTLGTS KDTVIALGPL
     IMGVVGAIVL IVTVIGLIRK AK